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The S492R EGFR ectodomain mutation is never detected in KRAS wild-type colorectal carcinoma before exposure to EGFR monoclonal antibodies.
Esposito C, Rachiglio AM, La Porta ML, Sacco A, Roma C, Iannaccone A, Tatangelo F, Forgione L, Pasquale R, Barbaro A, Botti G, Ciardiello F, Normanno N. Esposito C, et al. Among authors: sacco a. Cancer Biol Ther. 2013 Dec;14(12):1143-6. doi: 10.4161/cbt.26340. Epub 2013 Sep 23. Cancer Biol Ther. 2013. PMID: 24025416 Free PMC article.
EGFR mutations in lung cancer: from tissue testing to liquid biopsy.
Fenizia F, De Luca A, Pasquale R, Sacco A, Forgione L, Lambiase M, Iannaccone A, Chicchinelli N, Franco R, Rossi A, Morabito A, Rocco G, Piccirillo MC, Normanno N. Fenizia F, et al. Among authors: sacco a. Future Oncol. 2015;11(11):1611-23. doi: 10.2217/fon.15.23. Future Oncol. 2015. PMID: 26043215 Review.
Assessment of high-sensitive methods for the detection of EGFR mutations in circulating free tumor DNA from NSCLC patients.
Pasquale R, Fenizia F, Esposito Abate R, Sacco A, Esposito C, Forgione L, Rachiglio AM, Bevilacqua S, Montanino A, Franco R, Rocco G, Botti G, Denis MG, Morabito A, De Luca A, Normanno N. Pasquale R, et al. Among authors: sacco a. Pharmacogenomics. 2015;16(10):1135-48. doi: 10.2217/pgs.15.45. Epub 2015 Aug 7. Pharmacogenomics. 2015. PMID: 26249748
Limits and potential of targeted sequencing analysis of liquid biopsy in patients with lung and colon carcinoma.
Rachiglio AM, Esposito Abate R, Sacco A, Pasquale R, Fenizia F, Lambiase M, Morabito A, Montanino A, Rocco G, Romano C, Nappi A, Iaffaioli RV, Tatangelo F, Botti G, Ciardiello F, Maiello MR, De Luca A, Normanno N. Rachiglio AM, et al. Among authors: sacco a. Oncotarget. 2016 Oct 11;7(41):66595-66605. doi: 10.18632/oncotarget.10704. Oncotarget. 2016. PMID: 27448974 Free PMC article.
RAS testing of liquid biopsy correlates with the outcome of metastatic colorectal cancer patients treated with first-line FOLFIRI plus cetuximab in the CAPRI-GOIM trial.
Normanno N, Esposito Abate R, Lambiase M, Forgione L, Cardone C, Iannaccone A, Sacco A, Rachiglio AM, Martinelli E, Rizzi D, Pisconti S, Biglietto M, Bordonaro R, Troiani T, Latiano TP, Giuliani F, Leo S, Rinaldi A, Maiello E, Ciardiello F; CAPRI-GOIM Investigators. Normanno N, et al. Among authors: sacco a. Ann Oncol. 2018 Jan 1;29(1):112-118. doi: 10.1093/annonc/mdx417. Ann Oncol. 2018. PMID: 28950295 Free article. Clinical Trial.
Detection of EGFR Variants in Plasma: A Multilaboratory Comparison of a Real-Time PCR EGFR Mutation Test in Europe.
Keppens C, Palma JF, Das PM, Scudder S, Wen W, Normanno N, van Krieken JH, Sacco A, Fenizia F, Gonzalez de Castro D, Hönigschnabl S, Kern I, Lopez-Rios F, Lozano MD, Marchetti A, Halfon P, Schuuring E, Setinek U, Sorensen B, Taniere P, Tiemann M, Vosmikova H, Dequeker EMC. Keppens C, et al. Among authors: sacco a. J Mol Diagn. 2018 Jul;20(4):483-494. doi: 10.1016/j.jmoldx.2018.03.006. Epub 2018 Apr 26. J Mol Diagn. 2018. PMID: 29704571 Free article.
The role of circulating free DNA in the management of NSCLC.
Esposito Abate R, Pasquale R, Fenizia F, Rachiglio AM, Roma C, Bergantino F, Forgione L, Lambiase M, Sacco A, Piccirillo MC, Morabito A, Normanno N. Esposito Abate R, et al. Among authors: sacco a. Expert Rev Anticancer Ther. 2019 Jan;19(1):19-28. doi: 10.1080/14737140.2019.1548938. Epub 2018 Nov 29. Expert Rev Anticancer Ther. 2019. PMID: 30462523 Review.
The MITO CERV-2 trial: A randomized phase II study of cetuximab plus carboplatin and paclitaxel, in advanced or recurrent cervical cancer.
Pignata S, Scambia G, Lorusso D, De Giorgi U, Nicoletto MO, Lauria R, Mosconi AM, Sacco C, Omarini C, Tagliaferri P, Ferrandina G, Cinieri S, Savarese A, Valabrega G, Pisano C, Salutari V, Raspagliesi F, Kopf B, Cecere SC, Amadio G, Maltese G, Di Napoli M, Greggi S, Signoriello S, Daniele G, Sacco A, Losito S, Normanno N, Perrone F, Gallo C, Piccirillo MC; MITO Investigators. Pignata S, et al. Among authors: sacco c, sacco a. Gynecol Oncol. 2019 Jun;153(3):535-540. doi: 10.1016/j.ygyno.2019.03.260. Epub 2019 Apr 9. Gynecol Oncol. 2019. PMID: 30979589 Free article. Clinical Trial.
Liquid Biopsy Testing Can Improve Selection of Advanced Non-Small-Cell Lung Cancer Patients to Rechallenge with Gefitinib.
Esposito Abate R, Pasquale R, Sacco A, Piccirillo MC, Morabito A, Bidoli P, Finocchiaro G, Chiari R, Foltran L, Buosi R, Tiseo M, Giannetta L, Battiloro C, Fasola G, Romano G, Ciuffreda L, Frassoldati A, de Marinis F, Cappuzzo F, Normanno N. Esposito Abate R, et al. Among authors: sacco a. Cancers (Basel). 2019 Sep 25;11(10):1431. doi: 10.3390/cancers11101431. Cancers (Basel). 2019. PMID: 31557965 Free PMC article.
659 results