Colistin kills bacteria by targeting lipopolysaccharide in the cytoplasmic membrane.
Sabnis A, Hagart KL, Klöckner A, Becce M, Evans LE, Furniss RCD, Mavridou DA, Murphy R, Stevens MM, Davies JC, Larrouy-Maumus GJ, Clarke TB, Edwards AM.
Sabnis A, et al.
Elife. 2021 Apr 6;10:e65836. doi: 10.7554/eLife.65836.
Elife. 2021.
PMID: 33821795
Free PMC article.
Sabnis et al. examined the effects of colistin on Escherichia coli bacteria with and without resistance to the antibiotic. ...To find out whether this combination of colistin and murepavadin could work as a clinical treatment, Sabnis et al. tested it on mice …
Sabnis et al. examined the effects of colistin on Escherichia coli bacteria with and without resistance to the antibiotic. ...To find …