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Colistin kills bacteria by targeting lipopolysaccharide in the cytoplasmic membrane.
Sabnis A, Hagart KL, Klöckner A, Becce M, Evans LE, Furniss RCD, Mavridou DA, Murphy R, Stevens MM, Davies JC, Larrouy-Maumus GJ, Clarke TB, Edwards AM. Sabnis A, et al. Elife. 2021 Apr 6;10:e65836. doi: 10.7554/eLife.65836. Elife. 2021. PMID: 33821795 Free PMC article.
Sabnis et al. examined the effects of colistin on Escherichia coli bacteria with and without resistance to the antibiotic. ...To find out whether this combination of colistin and murepavadin could work as a clinical treatment, Sabnis et al. tested it on mice …
Sabnis et al. examined the effects of colistin on Escherichia coli bacteria with and without resistance to the antibiotic. ...To find …
Antibiotic interceptors: Creating safe spaces for bacteria.
Sabnis A, Ledger EVK, Pader V, Edwards AM. Sabnis A, et al. PLoS Pathog. 2018 Apr 19;14(4):e1006924. doi: 10.1371/journal.ppat.1006924. eCollection 2018 Apr. PLoS Pathog. 2018. PMID: 29672612 Free PMC article. No abstract available.
Costs and benefits of provocation in bacterial warfare.
Gonzalez D, Sabnis A, Foster KR, Mavridou DAI. Gonzalez D, et al. Among authors: sabnis a. Proc Natl Acad Sci U S A. 2018 Jul 17;115(29):7593-7598. doi: 10.1073/pnas.1801028115. Epub 2018 Jul 2. Proc Natl Acad Sci U S A. 2018. PMID: 29967163 Free PMC article.
Lipopolysaccharide as an antibiotic target.
Sabnis A, Edwards AM. Sabnis A, et al. Biochim Biophys Acta Mol Cell Res. 2023 Oct;1870(7):119507. doi: 10.1016/j.bbamcr.2023.119507. Epub 2023 Jun 1. Biochim Biophys Acta Mol Cell Res. 2023. PMID: 37268022 Free article. Review.
Integrated analysis of patient networks and plasmid genomes reveals a regional, multi-species outbreak of carbapenemase-producing Enterobacterales carrying both blaIMP and mcr-9 genes.
Wan Y, Myall AC, Boonyasiri A, Bolt F, Ledda A, Mookerjee S, Weiße AY, Getino M, Turton JF, Abbas H, Prakapaite R, Sabnis A, Abdolrasouli A, Malpartida-Cardenas K, Miglietta L, Donaldson H, Gilchrist M, Hopkins KL, Ellington MJ, Otter JA, Larrouy-Maumus G, Edwards AM, Rodriguez-Manzano J, Didelot X, Barahona M, Holmes AH, Jauneikaite E, Davies F. Wan Y, et al. Among authors: sabnis a. J Infect Dis. 2024 Jan 20:jiae019. doi: 10.1093/infdis/jiae019. Online ahead of print. J Infect Dis. 2024. PMID: 38245822
83 results