Sabirsh A - Search Results

1

Interaction Kinetics of Individual mRNA-Containing Lipid Nanoparticles with an Endosomal Membrane Mimic: Dependence on pH, Protein Corona Formation, and Lipoprotein Depletion.

Aliakbarinodehi N, Gallud A, Mapar M, Wesén E, Heydari S, Jing Y, Emilsson G, Liu K, Sabirsh A, Zhdanov VP, Lindfors L, Esbjörner EK, Höök F. Aliakbarinodehi N, et al. Among authors: sabirsh a. ACS Nano. 2022 Dec 27;16(12):20163-20173. doi: 10.1021/acsnano.2c04829. Epub 2022 Dec 13. ACS Nano. 2022. PMID: 36511601 Free PMC article.

2

A high-throughput Galectin-9 imaging assay for quantifying nanoparticle uptake, endosomal escape and functional RNA delivery.

Munson MJ, O'Driscoll G, Silva AM, Lázaro-Ibáñez E, Gallud A, Wilson JT, Collén A, Esbjörner EK, Sabirsh A. Munson MJ, et al. Among authors: sabirsh a. Commun Biol. 2021 Feb 16;4(1):211. doi: 10.1038/s42003-021-01728-8. Commun Biol. 2021. PMID: 33594247 Free PMC article.

3

Endosomal escape of delivered mRNA from endosomal recycling tubules visualized at the nanoscale.

Paramasivam P, Franke C, Stöter M, Höijer A, Bartesaghi S, Sabirsh A, Lindfors L, Arteta MY, Dahlén A, Bak A, Andersson S, Kalaidzidis Y, Bickle M, Zerial M. Paramasivam P, et al. Among authors: sabirsh a. J Cell Biol. 2022 Feb 7;221(2):e202110137. doi: 10.1083/jcb.202110137. Epub 2021 Dec 9. J Cell Biol. 2022. PMID: 34882187 Free PMC article.

4

Quantitative intracellular retention of delivered RNAs through optimized cell fixation and immunostaining.

Paramasivam P, Stöter M, Corradi E, Dalla Costa I, Höijer A, Bartesaghi S, Sabirsh A, Lindfors L, Yanez Arteta M, Nordberg P, Andersson S, Baudet ML, Bickle M, Zerial M. Paramasivam P, et al. Among authors: sabirsh a. RNA. 2022 Mar;28(3):433-446. doi: 10.1261/rna.078895.121. Epub 2021 Dec 23. RNA. 2022. PMID: 34949721 Free PMC article.

5

Physiology, pathology and the biomolecular corona: the confounding factors in nanomedicine design.

Liu K, Salvati A, Sabirsh A. Liu K, et al. Among authors: sabirsh a. Nanoscale. 2022 Feb 10;14(6):2136-2154. doi: 10.1039/d1nr08101b. Nanoscale. 2022. PMID: 35103268 Review.

6

Multiomics analysis of naturally efficacious lipid nanoparticle coronas reveals high-density lipoprotein is necessary for their function.

Liu K, Nilsson R, Lázaro-Ibáñez E, Duàn H, Miliotis T, Strimfors M, Lerche M, Salgado Ribeiro AR, Ulander J, Lindén D, Salvati A, Sabirsh A. Liu K, et al. Among authors: sabirsh a. Nat Commun. 2023 Jul 6;14(1):4007. doi: 10.1038/s41467-023-39768-9. Nat Commun. 2023. PMID: 37414857 Free PMC article.

7

Reply to: Technical challenges of studying the impact of plasma components on the efficacy of lipid nanoparticles for vaccine and therapeutic applications.

Liu K, Lázaro-Ibáñez E, Lerche M, Lindén D, Salvati A, Sabirsh A. Liu K, et al. Among authors: sabirsh a. Nat Commun. 2024 May 9;15(1):3853. doi: 10.1038/s41467-024-47726-2. Nat Commun. 2024. PMID: 38724506 Free PMC article. No abstract available.

8

High-Throughput Automation of Endosomolytic Polymers for mRNA Delivery.

Ulkoski D, Munson MJ, Jacobson ME, Palmer CR, Carson CS, Sabirsh A, Wilson JT, Krishnamurthy VR. Ulkoski D, et al. Among authors: sabirsh a. ACS Appl Bio Mater. 2021 Feb 15;4(2):1640-1654. doi: 10.1021/acsabm.0c01463. Epub 2021 Jan 19. ACS Appl Bio Mater. 2021. PMID: 35014512

9

Understanding Intracellular Biology to Improve mRNA Delivery by Lipid Nanoparticles.

Hunter MR, Cui L, Porebski BT, Pereira S, Sonzini S, Odunze U, Iyer P, Engkvist O, Lloyd RL, Peel S, Sabirsh A, Ross-Thriepland D, Jones AT, Desai AS. Hunter MR, et al. Among authors: sabirsh a. Small Methods. 2023 Sep;7(9):e2201695. doi: 10.1002/smtd.202201695. Epub 2023 Jun 14. Small Methods. 2023. PMID: 37317010 Free PMC article.

10

Effect of complexing lipids on cellular uptake and expression of messenger RNA in human skin explants.

Blakney AK, Deletic P, McKay PF, Bouton CR, Ashford M, Shattock RJ, Sabirsh A. Blakney AK, et al. Among authors: sabirsh a. J Control Release. 2021 Feb 10;330:1250-1261. doi: 10.1016/j.jconrel.2020.11.033. Epub 2020 Nov 26. J Control Release. 2021. PMID: 33250305 Free article.

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