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SUCNR1 regulates insulin secretion and glucose elevates the succinate response in people with prediabetes.
Sabadell-Basallote J, Astiarraga B, Castaño C, Ejarque M, Repollés-de-Dalmau M, Quesada I, Blanco J, Nuñez-Roa C, Rodríguez-Peña MM, Martínez L, De Jesus DF, Marroqui L, Bosch R, Montanya E, Sureda FX, Tura A, Mari A, Kulkarni RN, Vendrell J, Fernández-Veledo S. Sabadell-Basallote J, et al. J Clin Invest. 2024 May 7:e173214. doi: 10.1172/JCI173214. Online ahead of print. J Clin Invest. 2024. PMID: 38713514 Free article.
EndoC-βH5 cells are storable and ready-to-use human pancreatic beta cells with physiological insulin secretion.
Blanchi B, Taurand M, Colace C, Thomaidou S, Audeoud C, Fantuzzi F, Sawatani T, Gheibi S, Sabadell-Basallote J, Boot FWJ, Chantier T, Piet A, Cavanihac C, Pilette M, Balguerie A, Olleik H, Carlotti F, Ejarque M, Fex M, Mulder H, Cnop M, Eizirik DL, Jouannot O, Gaffuri AL, Czernichow P, Zaldumbide A, Scharfmann R, Ravassard P. Blanchi B, et al. Among authors: sabadell basallote j. Mol Metab. 2023 Oct;76:101772. doi: 10.1016/j.molmet.2023.101772. Epub 2023 Jul 11. Mol Metab. 2023. PMID: 37442376 Free PMC article.
SUCNR1 signaling in adipocytes controls energy metabolism by modulating circadian clock and leptin expression.
Villanueva-Carmona T, Cedó L, Madeira A, Ceperuelo-Mallafré V, Rodríguez-Peña MM, Núñez-Roa C, Maymó-Masip E, Repollés-de-Dalmau M, Badia J, Keiran N, Mirasierra M, Pimenta-Lopes C, Sabadell-Basallote J, Bosch R, Caubet L, Escolà-Gil JC, Fernández-Real JM, Vilarrasa N, Ventura F, Vallejo M, Vendrell J, Fernández-Veledo S. Villanueva-Carmona T, et al. Among authors: sabadell basallote j. Cell Metab. 2023 Apr 4;35(4):601-619.e10. doi: 10.1016/j.cmet.2023.03.004. Epub 2023 Mar 27. Cell Metab. 2023. PMID: 36977414 Free article.
Glycogen accumulation in adipocyte precursors from elderly and obese subjects triggers inflammation via SIRT1/6 signaling.
Terrón-Puig M, Huber-Ruano I, Sabadell-Basallote J, Ejarque M, Núñez-Roa C, Maymó-Masip E, Jorba R, Serena C, Vendrell J, Fernández-Veledo S. Terrón-Puig M, et al. Among authors: sabadell basallote j. Aging Cell. 2022 Aug;21(8):e13667. doi: 10.1111/acel.13667. Epub 2022 Jul 10. Aging Cell. 2022. PMID: 35811457 Free PMC article.
Effects of stem cells from inducible brown adipose tissue on diet-induced obesity in mice.
Calvo E, Keiran N, Núñez-Roa C, Maymó-Masip E, Ejarque M, Sabadell-Basallote J, Del Mar Rodríguez-Peña M, Ceperuelo-Mallafré V, Seco J, Benaiges E, Michalopoulou T, Jorba R, Vendrell J, Fernández-Veledo S. Calvo E, et al. Among authors: sabadell basallote j. Sci Rep. 2021 Jul 6;11(1):13923. doi: 10.1038/s41598-021-93224-6. Sci Rep. 2021. PMID: 34230537 Free PMC article.
Adipose tissue is a key organ for the beneficial effects of GLP-2 metabolic function.
Ejarque M, Sabadell-Basallote J, Beiroa D, Calvo E, Keiran N, Nuñez-Roa C, Rodríguez MDM, Sabench F, Del Castillo D, Jimenez V, Bosch F, Nogueiras R, Vendrell J, Fernández-Veledo S. Ejarque M, et al. Among authors: sabadell basallote j. Br J Pharmacol. 2021 May;178(10):2131-2145. doi: 10.1111/bph.15278. Epub 2020 Nov 19. Br J Pharmacol. 2021. PMID: 32986861 Free article.