Saarela J - Search Results

1

High Throughput siRNA Screening Using Reverse Transfection.

von Schantz C, Saarela J. von Schantz C, et al. Among authors: saarela j. Methods Mol Biol. 2016;1470:25-37. doi: 10.1007/978-1-4939-6337-9_3. Methods Mol Biol. 2016. PMID: 27581282

2

A novel aspartylglucosaminuria mutation affects translocation of aspartylglucosaminidase.

Saarela J, von Schantz C, Peltonen L, Jalanko A. Saarela J, et al. Hum Mutat. 2004 Oct;24(4):350-1. doi: 10.1002/humu.9276. Hum Mutat. 2004. PMID: 15365992

3

Glycosylation, transport, and complex formation of palmitoyl protein thioesterase 1 (PPT1)--distinct characteristics in neurons.

Lyly A, von Schantz C, Salonen T, Kopra O, Saarela J, Jauhiainen M, Kyttälä A, Jalanko A. Lyly A, et al. Among authors: saarela j. BMC Cell Biol. 2007 Jun 12;8:22. doi: 10.1186/1471-2121-8-22. BMC Cell Biol. 2007. PMID: 17565660 Free PMC article.

4

The high throughput biomedicine unit at the institute for molecular medicine Finland: high throughput screening meets precision medicine.

Pietiainen V, Saarela J, von Schantz C, Turunen L, Ostling P, Wennerberg K. Pietiainen V, et al. Among authors: saarela j. Comb Chem High Throughput Screen. 2014 May;17(4):377-86. doi: 10.2174/1386207317666140323195927. Comb Chem High Throughput Screen. 2014. PMID: 24661208

5

Discovery of MINC1, a GTPase-activating protein small molecule inhibitor, targeting MgcRacGAP.

van Adrichem AJ, Fagerholm A, Turunen L, Lehto A, Saarela J, Koskinen A, Repasky GA, Wennerberg K. van Adrichem AJ, et al. Among authors: saarela j. Comb Chem High Throughput Screen. 2015;18(1):3-17. doi: 10.2174/1386207318666141205112730. Comb Chem High Throughput Screen. 2015. PMID: 25479424 Free PMC article.

6

Methods for High-throughput Drug Combination Screening and Synergy Scoring.

He L, Kulesskiy E, Saarela J, Turunen L, Wennerberg K, Aittokallio T, Tang J. He L, et al. Among authors: saarela j. Methods Mol Biol. 2018;1711:351-398. doi: 10.1007/978-1-4939-7493-1_17. Methods Mol Biol. 2018. PMID: 29344898 Free PMC article.

7

Development of FRET-based high-throughput screening for viral RNase III inhibitors.

Wang L, Saarela J, Poque S, Valkonen JPT. Wang L, et al. Among authors: saarela j. Mol Plant Pathol. 2020 Jul;21(7):961-974. doi: 10.1111/mpp.12942. Epub 2020 May 21. Mol Plant Pathol. 2020. PMID: 32436305 Free PMC article.

8

High-throughput compound screening identifies navitoclax combined with irradiation as a candidate therapy for HPV-negative head and neck squamous cell carcinoma.

Tuomainen K, Hyytiäinen A, Al-Samadi A, Ianevski P, Ianevski A, Potdar S, Turunen L, Saarela J, Kuznetsov S, Wahbi W, Risteli M, Mäkitie A, Monni O, Salo T. Tuomainen K, et al. Among authors: saarela j. Sci Rep. 2021 Jul 20;11(1):14755. doi: 10.1038/s41598-021-94259-5. Sci Rep. 2021. PMID: 34285300 Free PMC article.

9

Genome-wide siRNA screening reveals several host receptors for the binding of human gut commensal Bifidobacterium bifidum.

Kainulainen V, von Schantz-Fant C, Kovanen RM, Potdar S, Laamanen K, Saarela J, Satokari R. Kainulainen V, et al. Among authors: saarela j. NPJ Biofilms Microbiomes. 2022 Jun 29;8(1):50. doi: 10.1038/s41522-022-00312-0. NPJ Biofilms Microbiomes. 2022. PMID: 35768415 Free PMC article.

10

Suppression of BRCA1 sensitizes cells to proteasome inhibitors.

Gu Y, Bouwman P, Greco D, Saarela J, Yadav B, Jonkers J, Kuznetsov SG. Gu Y, et al. Among authors: saarela j. Cell Death Dis. 2014 Dec 18;5(12):e1580. doi: 10.1038/cddis.2014.537. Cell Death Dis. 2014. PMID: 25522274 Free PMC article.

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