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Serine protease inhibitor kunitz-type 2 is downregulated in myelodysplastic syndromes and modulates cell-cell adhesion.
Roversi FM, Lopes MR, Machado-Neto JA, Longhini AL, Duarte Ada S, Baratti MO, Palodetto B, Corrocher FA, Pericole FV, Campos Pde M, Favaro P, Traina F, Saad ST. Roversi FM, et al. Stem Cells Dev. 2014 May 15;23(10):1109-20. doi: 10.1089/scd.2013.0441. Epub 2014 Feb 18. Stem Cells Dev. 2014. PMID: 24410667 Free PMC article. Clinical Trial.
Hematopoietic cell kinase (HCK) is a potential therapeutic target for dysplastic and leukemic cells due to integration of erythropoietin/PI3K pathway and regulation of erythropoiesis: HCK in erythropoietin/PI3K pathway.
Roversi FM, Pericole FV, Machado-Neto JA, da Silva Santos Duarte A, Longhini AL, Corrocher FA, Palodetto B, Ferro KP, Rosa RG, Baratti MO, Verjovski-Almeida S, Traina F, Molinari A, Botta M, Saad ST. Roversi FM, et al. Biochim Biophys Acta Mol Basis Dis. 2017 Feb;1863(2):450-461. doi: 10.1016/j.bbadis.2016.11.013. Epub 2016 Nov 11. Biochim Biophys Acta Mol Basis Dis. 2017. PMID: 27840303 Free article.
Up-regulation of SPINT2/HAI-2 by Azacytidine in bone marrow mesenchymal stromal cells affects leukemic stem cell survival and adhesion.
Roversi FM, Cury NM, Lopes MR, Ferro KP, Machado-Neto JA, Alvarez MC, Dos Santos GP, Giardini Rosa R, Longhini AL, Duarte ADSS, Pericole FV, Favaro P, Yunes JA, Saad STO. Roversi FM, et al. Among authors: saad sto. J Cell Mol Med. 2019 Feb;23(2):1562-1571. doi: 10.1111/jcmm.14066. Epub 2018 Nov 28. J Cell Mol Med. 2019. PMID: 30484958 Free PMC article.
229 results