Sałat K - Search Results

1

Structure-activity relationship study of tryptophan-based butyrylcholinesterase inhibitors.

Meden A, Knez D, Malikowska-Racia N, Brazzolotto X, Nachon F, Svete J, Sałat K, Grošelj U, Gobec S. Meden A, et al. Among authors: salat k. Eur J Med Chem. 2020 Dec 15;208:112766. doi: 10.1016/j.ejmech.2020.112766. Epub 2020 Aug 22. Eur J Med Chem. 2020. PMID: 32919297

2

Synthesis, biological evaluation and structure-activity relationship of new GABA uptake inhibitors, derivatives of 4-aminobutanamides.

Kowalczyk P, Sałat K, Höfner GC, Mucha M, Rapacz A, Podkowa A, Filipek B, Wanner KT, Kulig K. Kowalczyk P, et al. Among authors: salat k. Eur J Med Chem. 2014 Aug 18;83:256-73. doi: 10.1016/j.ejmech.2014.06.024. Epub 2014 Jun 12. Eur J Med Chem. 2014. PMID: 24973660

3

Synthesis of new N-benzylpiperidine derivatives as cholinesterase inhibitors with β-amyloid anti-aggregation properties and beneficial effects on memory in vivo.

Więckowska A, Więckowski K, Bajda M, Brus B, Sałat K, Czerwińska P, Gobec S, Filipek B, Malawska B. Więckowska A, et al. Among authors: salat k. Bioorg Med Chem. 2015 May 15;23(10):2445-57. doi: 10.1016/j.bmc.2015.03.051. Epub 2015 Mar 27. Bioorg Med Chem. 2015. PMID: 25868744

4

Synthesis, and anticonvulsant activity of new amides derived from 3-methyl- or 3-ethyl-3-methyl-2,5-dioxo-pyrrolidin-1-yl-acetic acids.

Obniska J, Rapacz A, Rybka S, Góra M, Kamiński K, Sałat K, Żmudzki P. Obniska J, et al. Among authors: salat k. Bioorg Med Chem. 2016 Apr 15;24(8):1598-607. doi: 10.1016/j.bmc.2016.02.026. Epub 2016 Feb 27. Bioorg Med Chem. 2016. PMID: 26970661

5

Development of an in-vivo active reversible butyrylcholinesterase inhibitor.

Košak U, Brus B, Knez D, Šink R, Žakelj S, Trontelj J, Pišlar A, Šlenc J, Gobec M, Živin M, Tratnjek L, Perše M, Sałat K, Podkowa A, Filipek B, Nachon F, Brazzolotto X, Więckowska A, Malawska B, Stojan J, Raščan IM, Kos J, Coquelle N, Colletier JP, Gobec S. Košak U, et al. Among authors: salat k. Sci Rep. 2016 Dec 21;6:39495. doi: 10.1038/srep39495. Sci Rep. 2016. PMID: 28000737 Free PMC article.

6

The Magic of Crystal Structure-Based Inhibitor Optimization: Development of a Butyrylcholinesterase Inhibitor with Picomolar Affinity and in Vivo Activity.

Košak U, Brus B, Knez D, Žakelj S, Trontelj J, Pišlar A, Šink R, Jukič M, Živin M, Podkowa A, Nachon F, Brazzolotto X, Stojan J, Kos J, Coquelle N, Sałat K, Colletier JP, Gobec S. Košak U, et al. Among authors: salat k. J Med Chem. 2018 Jan 11;61(1):119-139. doi: 10.1021/acs.jmedchem.7b01086. Epub 2017 Dec 22. J Med Chem. 2018. PMID: 29227101

7

Phencyclidine and Scopolamine for Modeling Amnesia in Rodents: Direct Comparison with the Use of Barnes Maze Test and Contextual Fear Conditioning Test in Mice.

Malikowska-Racia N, Podkowa A, Sałat K. Malikowska-Racia N, et al. Among authors: salat k. Neurotox Res. 2018 Oct;34(3):431-441. doi: 10.1007/s12640-018-9901-7. Epub 2018 Apr 21. Neurotox Res. 2018. PMID: 29680979 Free PMC article.

8

Novel amide derivatives of 1,3-dimethyl-2,6-dioxopurin-7-yl-alkylcarboxylic acids as multifunctional TRPA1 antagonists and PDE4/7 inhibitors: A new approach for the treatment of pain.

Chłoń-Rzepa G, Ślusarczyk M, Jankowska A, Gawalska A, Bucki A, Kołaczkowski M, Świerczek A, Pociecha K, Wyska E, Zygmunt M, Kazek G, Sałat K, Pawłowski M. Chłoń-Rzepa G, et al. Among authors: salat k. Eur J Med Chem. 2018 Oct 5;158:517-533. doi: 10.1016/j.ejmech.2018.09.021. Epub 2018 Sep 10. Eur J Med Chem. 2018. PMID: 30245393

9

Recent advances in the neurobiology of posttraumatic stress disorder: A review of possible mechanisms underlying an effective pharmacotherapy.

Malikowska-Racia N, Salat K. Malikowska-Racia N, et al. Among authors: salat k. Pharmacol Res. 2019 Apr;142:30-49. doi: 10.1016/j.phrs.2019.02.001. Epub 2019 Feb 8. Pharmacol Res. 2019. PMID: 30742899 Review.

10

Searching for analgesic drug candidates alleviating oxaliplatin-induced cold hypersensitivity in mice.

Sałat K, Furgała A, Malikowska-Racia N. Sałat K, et al. Chem Biol Drug Des. 2019 Jun;93(6):1061-1072. doi: 10.1111/cbdd.13507. Epub 2019 Mar 22. Chem Biol Drug Des. 2019. PMID: 30900821

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