Additionally, the percentages of T-cells (CD4(+), CD8(+)) and dendritic cell phenotypes (CD83(+), CD86(+)) were significantly elevated (** p < 0.01, *** p < 0.001) in mice inoculated with the nanovaccine compared to control groups and the rHcES-15 group. Correspondin
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PLGA-Encapsulated Haemonchus contortus Antigen ES-15 Augments Immune Responses in a Murine Model.
Vaccines (Basel). 2023 Nov 30;11(12):1794. doi: 10.3390/vaccines11121794.
Vaccines (Basel). 2023.
PMID: 38140198
Free PMC article.
Additionally, the percentages of T-cells (CD4(+), CD8(+)) and dendritic cell phenotypes (CD83(+), CD86(+)) were significantly elevated (** p …
Haemonchus contortus HcL6 promoted the Th9 immune response in goat PBMCs by activating the STAT6/PU.1/NF-κB pathway.
Liang M, Zhang Y, Wang M, Wen Z, Chen C, Bu Y, Lu M, Song X, Xu L, Li X, Yan R.
Liang M, et al.
Vet Res. 2023 Sep 22;54(1):80. doi: 10.1186/s13567-023-01214-5.
Vet Res. 2023.
PMID: 37740213
Free PMC article.
The development of Th9 cells is facilitated by several cytokines. Key transcription factors, such as STAT6, STAT5, and PU.1, are known to enhance IL-9 expression during the Th9 immune response. ...The observations revealed the transcriptional upregulation of several key …
The development of Th9 cells is facilitated by several cytokines. Key transcription factors, such as STAT6, STAT5, and PU.1, are know …
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