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Discovery of the First-in-Class G9a/GLP PROTAC Degrader.
Velez J, Han Y, Yim H, Yang P, Deng Z, Park KS, Kabir M, Kaniskan HÜ, Xiong Y, Jin J. Velez J, et al. J Med Chem. 2024 Apr 25;67(8):6397-6409. doi: 10.1021/acs.jmedchem.3c02394. Epub 2024 Apr 11. J Med Chem. 2024. PMID: 38602846
Discovery of a Potent, Selective, and Cell-Active SPIN1 Inhibitor.
Xiong Y, Greschik H, Johansson C, Seifert L, Gamble V, Park KS, Fagan V, Li F, Chau I, Vedadi M, Arrowsmith CH, Brennan P, Fedorov O, Jung M, Farnie G, Liu J, Oppermann U, Schüle R, Jin J. Xiong Y, et al. J Med Chem. 2024 Apr 11;67(7):5837-5853. doi: 10.1021/acs.jmedchem.4c00121. Epub 2024 Mar 27. J Med Chem. 2024. PMID: 38533580
Discovery of the First-in-class G9a/GLP PROTAC Degrader.
Velez J, Han Y, Yim H, Yang P, Deng Z, Park KS, Kabir M, Kaniskan HÜ, Xiong Y, Jin J. Velez J, et al. bioRxiv [Preprint]. 2024 Feb 29:2024.02.26.582210. doi: 10.1101/2024.02.26.582210. bioRxiv. 2024. PMID: 38464025 Free PMC article. Updated. Preprint.
40 results