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2017 14
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2023 9
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Immunization of cows with HIV envelope trimers generates broadly neutralizing antibodies to the V2-apex from the ultralong CDRH3 repertoire.
Altman PX, Ozorowski G, Stanfield RL, Haakenson J, Appel M, Parren M, Lee WH, Sang H, Woehl J, Saye-Francisco K, Joyce C, Song G, Porter K, Landais E, Andrabi R, Wilson IA, Ward AB, Mwangi W, Smider VV, Burton DR, Sok D. Altman PX, et al. bioRxiv [Preprint]. 2024 Feb 14:2024.02.13.580058. doi: 10.1101/2024.02.13.580058. bioRxiv. 2024. PMID: 38405899 Free PMC article. Preprint.
De novo design of knotted tandem repeat proteins.
Doyle LA, Takushi B, Kibler RD, Milles LF, Orozco CT, Jones JD, Jackson SE, Stoddard BL, Bradley P. Doyle LA, et al. Nat Commun. 2023 Oct 24;14(1):6746. doi: 10.1038/s41467-023-42388-y. Nat Commun. 2023. PMID: 37875492 Free PMC article.
Computational design of sequence-specific DNA-binding proteins.
Glasscock CJ, Pecoraro R, McHugh R, Doyle LA, Chen W, Boivin O, Lonnquist B, Na E, Politanska Y, Haddox HK, Cox D, Norn C, Coventry B, Goreshnik I, Vafeados D, Lee GR, Gordan R, Stoddard BL, DiMaio F, Baker D. Glasscock CJ, et al. bioRxiv [Preprint]. 2023 Sep 21:2023.09.20.558720. doi: 10.1101/2023.09.20.558720. bioRxiv. 2023. PMID: 37790440 Free PMC article. Preprint.
The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2.
Huang R, Warner Jenkins G, Kim Y, Stanfield RL, Singh A, Martinez-Yamout M, Kroon GJ, Torres JL, Jackson AM, Kelley A, Shaabani N, Zeng B, Bacica M, Chen W, Warner C, Radoicic J, Joh J, Dinali Perera K, Sang H, Kim T, Yao J, Zhao F, Sok D, Burton DR, Allen J, Harriman W, Mwangi W, Chung D, Teijaro JR, Ward AB, Dyson HJ, Wright PE, Wilson IA, Chang KO, McGregor D, Smider VV. Huang R, et al. Proc Natl Acad Sci U S A. 2023 Sep 26;120(39):e2303455120. doi: 10.1073/pnas.2303455120. Epub 2023 Sep 18. Proc Natl Acad Sci U S A. 2023. PMID: 37722054 Free PMC article.
A biophysical framework for double-drugging kinases.
Kim C, Ludewig H, Hadzipasic A, Kutter S, Nguyen V, Kern D. Kim C, et al. Proc Natl Acad Sci U S A. 2023 Aug 22;120(34):e2304611120. doi: 10.1073/pnas.2304611120. Epub 2023 Aug 17. Proc Natl Acad Sci U S A. 2023. PMID: 37590418 Free PMC article.
A biophysical framework for double-drugging kinases.
Kim C, Ludewig H, Hadzipasic A, Kutter S, Nguyen V, Kern D. Kim C, et al. bioRxiv [Preprint]. 2023 Mar 18:2023.03.17.533217. doi: 10.1101/2023.03.17.533217. bioRxiv. 2023. PMID: 36993258 Free PMC article. Updated. Preprint.
116 results