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Sestrin 2 protein regulates platelet-derived growth factor receptor β (Pdgfrβ) expression by modulating proteasomal and Nrf2 transcription factor functions.
Tomasovic A, Kurrle N, Sürün D, Heidler J, Husnjak K, Poser I, Schnütgen F, Scheibe S, Seimetz M, Jaksch P, Hyman A, Weissmann N, von Melchner H. Tomasovic A, et al. Among authors: surun d. J Biol Chem. 2015 Apr 10;290(15):9738-52. doi: 10.1074/jbc.M114.632133. Epub 2015 Feb 25. J Biol Chem. 2015. PMID: 25716320 Free PMC article.
Characterization and cellular localization of human 5-lipoxygenase and its protein isoforms 5-LOΔ13, 5-LOΔ4 and 5-LOp12.
Ball AK, Beilstein K, Wittmann S, Sürün D, Saul MJ, Schnütgen F, Flamand N, Capelo R, Kahnt AS, Frey H, Schaefer L, Marschalek R, Häfner AK, Steinhilber D. Ball AK, et al. Among authors: surun d. Biochim Biophys Acta Mol Cell Biol Lipids. 2017 May;1862(5):561-571. doi: 10.1016/j.bbalip.2017.02.015. Epub 2017 Feb 28. Biochim Biophys Acta Mol Cell Biol Lipids. 2017. PMID: 28257804
Stable Oxidative Cytosine Modifications Accumulate in Cardiac Mesenchymal Cells From Type2 Diabetes Patients: Rescue by α-Ketoglutarate and TET-TDG Functional Reactivation.
Spallotta F, Cencioni C, Atlante S, Garella D, Cocco M, Mori M, Mastrocola R, Kuenne C, Guenther S, Nanni S, Azzimato V, Zukunft S, Kornberger A, Sürün D, Schnütgen F, von Melchner H, Di Stilo A, Aragno M, Braspenning M, van Criekinge W, De Blasio MJ, Ritchie RH, Zaccagnini G, Martelli F, Farsetti A, Fleming I, Braun T, Beiras-Fernandez A, Botta B, Collino M, Bertinaria M, Zeiher AM, Gaetano C. Spallotta F, et al. Among authors: surun d. Circ Res. 2018 Jan 5;122(1):31-46. doi: 10.1161/CIRCRESAHA.117.311300. Epub 2017 Nov 20. Circ Res. 2018. PMID: 29158345 Free article.
Zeb1-Hdac2-eNOS circuitry identifies early cardiovascular precursors in naive mouse embryonic stem cells.
Cencioni C, Spallotta F, Savoia M, Kuenne C, Guenther S, Re A, Wingert S, Rehage M, Sürün D, Siragusa M, Smith JG, Schnütgen F, von Melchner H, Rieger MA, Martelli F, Riccio A, Fleming I, Braun T, Zeiher AM, Farsetti A, Gaetano C. Cencioni C, et al. Among authors: surun d. Nat Commun. 2018 Mar 29;9(1):1281. doi: 10.1038/s41467-018-03668-0. Nat Commun. 2018. PMID: 29599503 Free PMC article.
Sphingosine-1-phosphate (S1P) induces potent anti-inflammatory effects in vitro and in vivo by S1P receptor 4-mediated suppression of 5-lipoxygenase activity.
Fettel J, Kühn B, Guillen NA, Sürün D, Peters M, Bauer R, Angioni C, Geisslinger G, Schnütgen F, Meyer Zu Heringdorf D, Werz O, Meybohm P, Zacharowski K, Steinhilber D, Roos J, Maier TJ. Fettel J, et al. Among authors: surun d. FASEB J. 2019 Feb;33(2):1711-1726. doi: 10.1096/fj.201800221R. Epub 2018 Sep 6. FASEB J. 2019. PMID: 30188757
Furthermore, agonism at S1P4 represents a novel effective strategy in pharmacotherapy of inflammation.-Fettel, J., Kuhn, B., Guillen, N. A., Surun, D., Peters, M., Bauer, R., Angioni, C., Geisslinger, G., Schnutgen, F., Meyer zu Heringdorf, D., Werz, O., Meyb …
Furthermore, agonism at S1P4 represents a novel effective strategy in pharmacotherapy of inflammation.-Fettel, J., Kuhn, B., Guillen, N. A., …
CRISPR/Cas9 genome engineering in hematopoietic cells.
Sürün D, von Melchner H, Schnütgen F. Sürün D, et al. Drug Discov Today Technol. 2018 Aug;28:33-39. doi: 10.1016/j.ddtec.2018.08.001. Epub 2018 Aug 25. Drug Discov Today Technol. 2018. PMID: 30205879 Free article. Review.
α-ketoglutarate dehydrogenase inhibition counteracts breast cancer-associated lung metastasis.
Atlante S, Visintin A, Marini E, Savoia M, Dianzani C, Giorgis M, Sürün D, Maione F, Schnütgen F, Farsetti A, Zeiher AM, Bertinaria M, Giraudo E, Spallotta F, Cencioni C, Gaetano C. Atlante S, et al. Among authors: surun d. Cell Death Dis. 2018 Jul 9;9(7):756. doi: 10.1038/s41419-018-0802-8. Cell Death Dis. 2018. PMID: 29988033 Free PMC article.
22 results