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Influenza virus NS1 protein binds cellular DNA to block transcription of antiviral genes.
Anastasina M, Le May N, Bugai A, Fu Y, Söderholm S, Gaelings L, Ohman T, Tynell J, Kyttänen S, Barboric M, Nyman TA, Matikainen S, Julkunen I, Butcher SJ, Egly JM, Kainov DE. Anastasina M, et al. Among authors: soderholm s. Biochim Biophys Acta. 2016 Nov;1859(11):1440-1448. doi: 10.1016/j.bbagrm.2016.09.005. Epub 2016 Sep 21. Biochim Biophys Acta. 2016. PMID: 27664935
Regulation of kynurenine biosynthesis during influenza virus infection.
Gaelings L, Söderholm S, Bugai A, Fu Y, Nandania J, Schepens B, Lorey MB, Tynell J, Vande Ginste L, Le Goffic R, Miller MS, Kuisma M, Marjomäki V, De Brabander J, Matikainen S, Nyman TA, Bamford DH, Saelens X, Julkunen I, Paavilainen H, Hukkanen V, Velagapudi V, Kainov DE. Gaelings L, et al. Among authors: soderholm s. FEBS J. 2017 Jan;284(2):222-236. doi: 10.1111/febs.13966. Epub 2016 Dec 14. FEBS J. 2017. PMID: 27860276 Free article.
Akt inhibitor MK2206 prevents influenza pH1N1 virus infection in vitro.
Denisova OV, Söderholm S, Virtanen S, Von Schantz C, Bychkov D, Vashchinkina E, Desloovere J, Tynell J, Ikonen N, Theisen LL, Nyman TA, Matikainen S, Kallioniemi O, Julkunen I, Muller CP, Saelens X, Verkhusha VV, Kainov DE. Denisova OV, et al. Among authors: soderholm s. Antimicrob Agents Chemother. 2014 Jul;58(7):3689-96. doi: 10.1128/AAC.02798-13. Epub 2014 Apr 21. Antimicrob Agents Chemother. 2014. PMID: 24752266 Free PMC article.
Phosphoproteomics combined with quantitative 14-3-3-affinity capture identifies SIRT1 and RAI as novel regulators of cytosolic double-stranded RNA recognition pathway.
Öhman T, Söderholm S, Hintsanen P, Välimäki E, Lietzén N, MacKintosh C, Aittokallio T, Matikainen S, Nyman TA. Öhman T, et al. Among authors: soderholm s. Mol Cell Proteomics. 2014 Oct;13(10):2604-17. doi: 10.1074/mcp.M114.038968. Epub 2014 Jul 5. Mol Cell Proteomics. 2014. PMID: 24997996 Free PMC article.
69 results