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Tumor-neutrophil crosstalk promotes in vitro and in vivo glioblastoma progression.
Rubenich DS, de Souza PO, Omizzollo N, Aubin MR, Basso PJ, Silva LM, da Silva EM, Teixeira FC, Gentil GFS, Domagalski JL, Cunha MT, Gadelha KA, Diel LF, Gelsleichter NE, Rubenich AS, Lenz GS, de Abreu AM, Kroeff GM, Paz AH, Visioli F, Lamers ML, Wink MR, Worm PV, Araújo AB, Sévigny J, Câmara NOS, Ludwig N, Braganhol E. Rubenich DS, et al. Among authors: sevigny j. Front Immunol. 2023 May 24;14:1183465. doi: 10.3389/fimmu.2023.1183465. eCollection 2023. Front Immunol. 2023. PMID: 37292196 Free PMC article.
Heparins are potent inhibitors of ectonucleotide pyrophosphatase/phospho-diesterase-1 (NPP1) - a promising target for the immunotherapy of cancer.
Lopez V, Schuh HJM, Mirza S, Vaaßen VJ, Schmidt MS, Sylvester K, Idris RM, Renn C, Schäkel L, Pelletier J, Sévigny J, Naggi A, Scheffler B, Lee SY, Bendas G, Müller CE. Lopez V, et al. Among authors: sevigny j. Front Immunol. 2023 Aug 29;14:1173634. doi: 10.3389/fimmu.2023.1173634. eCollection 2023. Front Immunol. 2023. PMID: 37711611 Free PMC article.
Design and synthesis of new adamantyl derivatives as promising antiproliferative agents.
Shahin AI, Zaraei SO, AlKubaisi BO, Ullah S, Anbar HS, El-Gamal R, Menon V, Abdel-Maksoud MS, Oh CH, El-Awady R, Gelsleichter NE, Pelletier J, Sévigny J, Iqbal J, Al-Tel TH, El-Gamal MI. Shahin AI, et al. Among authors: sevigny j. Eur J Med Chem. 2023 Jan 15;246:114958. doi: 10.1016/j.ejmech.2022.114958. Epub 2022 Nov 26. Eur J Med Chem. 2023. PMID: 36470105
Extracellular nucleotides in smooth muscle contraction.
Babou Kammoe RB, Sévigny J. Babou Kammoe RB, et al. Among authors: sevigny j. Biochem Pharmacol. 2024 Feb;220:116005. doi: 10.1016/j.bcp.2023.116005. Epub 2023 Dec 22. Biochem Pharmacol. 2024. PMID: 38142836 Review.
Leishmania infantum NTPDase1 and NTPDase2 play an important role in infection and nitric oxide production in macrophages.
da Silva W, Ribeiro IC, Agripino JM, da Silva VHF, de Souza LÂ, Oliveira TA, Bressan GC, Vasconcellos RS, Dumas C, Pelletier J, Sévigny J, Papadopoulou B, Fietto JLR. da Silva W, et al. Among authors: sevigny j. Acta Trop. 2023 Jan;237:106732. doi: 10.1016/j.actatropica.2022.106732. Epub 2022 Oct 27. Acta Trop. 2023. PMID: 36309108 Free article.
350 results