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Page 1
Showing results for severe ld
Search for Séverine LD instead (3 results)
Severe Legionnaires' disease.
Rello J, Allam C, Ruiz-Spinelli A, Jarraud S. Rello J, et al. Ann Intensive Care. 2024 Apr 2;14(1):51. doi: 10.1186/s13613-024-01252-y. Ann Intensive Care. 2024. PMID: 38565811 Free PMC article. Review.
Mortality in ICU patients, immunocompromised patients or patients with a nosocomial source of LD can reach 40% despite appropriate antimicrobial therapy. Regarding pathogenesis, no Legionella-specific virulence factors have been associated with severity; however, re …
Mortality in ICU patients, immunocompromised patients or patients with a nosocomial source of LD can reach 40% despite appropriate an …
Secukinumab demonstrates high efficacy and a favourable safety profile in paediatric patients with severe chronic plaque psoriasis: 52-week results from a Phase 3 double-blind randomized, controlled trial.
Bodemer C, Kaszuba A, Kingo K, Tsianakas A, Morita A, Rivas E, Papanastasiou P, Keefe D, Patekar M, Charef P, Zhang L, Cafoncelli S, Papavassilis C. Bodemer C, et al. J Eur Acad Dermatol Venereol. 2021 Apr;35(4):938-947. doi: 10.1111/jdv.17002. Epub 2021 Jan 19. J Eur Acad Dermatol Venereol. 2021. PMID: 33068444 Free PMC article. Clinical Trial.
OBJECTIVES: Here, the efficacy and safety of two secukinumab dosing regimens [low dose (LD) and high dose (HD)] in paediatric patients with severe chronic plaque psoriasis over one year are reported. ...The efficacy of both doses was sustained to Week 52 with secuki …
OBJECTIVES: Here, the efficacy and safety of two secukinumab dosing regimens [low dose (LD) and high dose (HD)] in paediatric patient …
Efficacy and Safety of Lebrikizumab, a High-Affinity Interleukin 13 Inhibitor, in Adults With Moderate to Severe Atopic Dermatitis: A Phase 2b Randomized Clinical Trial.
Guttman-Yassky E, Blauvelt A, Eichenfield LF, Paller AS, Armstrong AW, Drew J, Gopalan R, Simpson EL. Guttman-Yassky E, et al. JAMA Dermatol. 2020 Apr 1;156(4):411-420. doi: 10.1001/jamadermatol.2020.0079. JAMA Dermatol. 2020. PMID: 32101256 Free PMC article. Clinical Trial.
Participants were adults 18 years or older with moderate to severe AD. INTERVENTIONS: Patients were randomized 2:3:3:3 to placebo every 2 weeks or to subcutaneous injections of lebrikizumab at the following doses: 125 mg every 4 weeks (250-mg loading dose [LD]), 250 …
Participants were adults 18 years or older with moderate to severe AD. INTERVENTIONS: Patients were randomized 2:3:3:3 to placebo eve …
Lipodystrophy: Syndrome of severe insulin resistance.
Bindlish S, Presswala LS, Schwartz F. Bindlish S, et al. Postgrad Med. 2015 Jun;127(5):511-6. doi: 10.1080/00325481.2015.1015927. Epub 2015 Feb 17. Postgrad Med. 2015. PMID: 25690482 Review.
CONTEXT: Lipodystrophy (LD) is a relatively rare complex collection of diseases that can be congenital or acquired. ...The search terms were lipodystrophy, congenital LD, acquired LD, HIV-associated LD, severe insulin resistance, adiposity, obes …
CONTEXT: Lipodystrophy (LD) is a relatively rare complex collection of diseases that can be congenital or acquired. ...The search ter …
Learning disabilities.
Lyon GR. Lyon GR. Future Child. 1996 Spring;6(1):54-76. Future Child. 1996. PMID: 8689262 Review.
The "real" prevalence of LD is subject to much dispute because of the lack of an agreed-upon definition of LD with objective identification criteria. ...Children with severe learning disabilities are likely to manifest an increased number of and increased …
The "real" prevalence of LD is subject to much dispute because of the lack of an agreed-upon definition of LD with objective i …
Exercise regulation of hepatic lipid droplet metabolism.
Pino-de la Fuente F, Bórquez JC, Díaz-Castro F, Espinosa A, Chiong M, Troncoso R. Pino-de la Fuente F, et al. Life Sci. 2022 Jun 1;298:120522. doi: 10.1016/j.lfs.2022.120522. Epub 2022 Mar 30. Life Sci. 2022. PMID: 35367244 Review.
The imbalance of LD function causes non-alcoholic fatty liver disease (NAFLD). Studies show that exercise attenuates NAFLD by decreasing LD content; however, reports show metabolic benefits without changes in LD amount (intrahepatic triglyceride levels) in NA …
The imbalance of LD function causes non-alcoholic fatty liver disease (NAFLD). Studies show that exercise attenuates NAFLD by decreas …
Genetic variety of ORF3a shapes SARS-CoV-2 fitness through modulation of lipid droplet.
Wang W, Qu Y, Wang X, Xiao MZX, Fu J, Chen L, Zheng Y, Liang Q. Wang W, et al. J Med Virol. 2023 Mar;95(3):e28630. doi: 10.1002/jmv.28630. J Med Virol. 2023. PMID: 36861654
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection leads to the accumulation of lipid droplets (LD), the central hubs of the lipid metabolism, in vitro or in type II pneumocytes and monocytes from coronavirus disease 19 (COVID-19) patients and bl …
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection leads to the accumulation of lipid droplets (LD), the c …
[Lafora's disease (EPM2)].
Genton P. Genton P. Rev Neurol (Paris). 2007 Jan;163(1):47-53. doi: 10.1016/s0035-3787(07)90354-9. Rev Neurol (Paris). 2007. PMID: 17304172 Review. French.
Lafora's disease (LD) is a comparatively frequent and particularly severe type of progressive myoclonus epilepsy. ...The treatment of LD remains purely symptomatic. Drugs that may aggravate myoclonus must be avoided. ...
Lafora's disease (LD) is a comparatively frequent and particularly severe type of progressive myoclonus epilepsy. ...The treat …
Efficacy of Secukinumab Across Subgroups and Overall Safety in Pediatric Patients with Moderate to Severe Plaque Psoriasis: Week 52 Results from a Phase III Randomized Study.
Magnolo N, Kingo K, Laquer V, Browning J, Reich A, Szepietowski JC, Keefe D, Papanastasiou P, Bao W, Forrer P, Patekar M. Magnolo N, et al. Paediatr Drugs. 2022 Jul;24(4):377-387. doi: 10.1007/s40272-022-00507-0. Epub 2022 Jun 13. Paediatr Drugs. 2022. PMID: 35698000 Free PMC article. Clinical Trial.
OBJECTIVE: We report the efficacy and safety of secukinumab low dose (LD) and high dose (HD) regimens in pediatric patients with moderate to severe psoriasis for up to Week 52. ...The proportions of IGA 0/1 and PASI 75/90 responders were comparable for the age, body …
OBJECTIVE: We report the efficacy and safety of secukinumab low dose (LD) and high dose (HD) regimens in pediatric patients with mode …
Hyper-inflammatory profile and immunoparalysis in patients with severe Legionnaires' disease.
Allam C, Mouton W, Testaert H, Ginevra C, Fessy N, Ibranosyan M, Descours G, Beraud L, Guillemot J, Chapalain A, Albert-Vega C, Richard JC, Argaud L, Friggeri A, Labeye V, Jamilloux Y, Freymond N, Venet F, Lina G, Doublet P, Ader F, Trouillet-Assant S, Jarraud S. Allam C, et al. Front Cell Infect Microbiol. 2023 Oct 27;13:1252515. doi: 10.3389/fcimb.2023.1252515. eCollection 2023. Front Cell Infect Microbiol. 2023. PMID: 37965258 Free PMC article.
INTRODUCTION: Severe Legionnaires' disease (LD) can lead to multi-organ failure or death in 10%-30% of patients. Although hyper-inflammation and immunoparalysis are well described in sepsis and are associated with high disease severity, little is known about …
INTRODUCTION: Severe Legionnaires' disease (LD) can lead to multi-organ failure or death in 10%-30% of patients. Although hype …
3,100 results