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The ellagic acid derivative 4,4'-di-O-methylellagic acid efficiently inhibits colon cancer cell growth through a mechanism involving WNT16.
Ramírez de Molina A, Vargas T, Molina S, Sánchez J, Martínez-Romero J, González-Vallinas M, Martín-Hernández R, Sánchez-Martínez R, Gómez de Cedrón M, Dávalos A, Calani L, Del Rio D, González-Sarrías A, Espín JC, Tomás-Barberán FA, Reglero G. Ramírez de Molina A, et al. J Pharmacol Exp Ther. 2015 May;353(2):433-44. doi: 10.1124/jpet.114.221796. Epub 2015 Mar 10. J Pharmacol Exp Ther. 2015. PMID: 25758919
A link between lipid metabolism and epithelial-mesenchymal transition provides a target for colon cancer therapy.
Sánchez-Martínez R, Cruz-Gil S, Gómez de Cedrón M, Álvarez-Fernández M, Vargas T, Molina S, García B, Herranz J, Moreno-Rubio J, Reglero G, Pérez-Moreno M, Feliu J, Malumbres M, Ramírez de Molina A. Sánchez-Martínez R, et al. Oncotarget. 2015 Nov 17;6(36):38719-36. doi: 10.18632/oncotarget.5340. Oncotarget. 2015. PMID: 26451612 Free PMC article.
MicroRNA-661 modulates redox and metabolic homeostasis in colon cancer.
Gómez de Cedrón M, Acín Pérez R, Sánchez-Martínez R, Molina S, Herranz J, Feliu J, Reglero G, Enríquez JA, Ramírez de Molina A. Gómez de Cedrón M, et al. Mol Oncol. 2017 Dec;11(12):1768-1787. doi: 10.1002/1878-0261.12142. Epub 2017 Nov 6. Mol Oncol. 2017. PMID: 28981199 Free PMC article.
Metabolic enzyme ACSL3 is a prognostic biomarker and correlates with anticancer effectiveness of statins in non-small cell lung cancer.
Fernández LP, Merino M, Colmenarejo G, Moreno-Rubio J, Sánchez-Martínez R, Quijada-Freire A, Gómez de Cedrón M, Reglero G, Casado E, Sereno M, Ramírez de Molina A. Fernández LP, et al. Mol Oncol. 2020 Dec;14(12):3135-3152. doi: 10.1002/1878-0261.12816. Epub 2020 Oct 30. Mol Oncol. 2020. PMID: 33030783 Free PMC article.
Lipid metabolism and lung cancer.
Merino Salvador M, Gómez de Cedrón M, Moreno Rubio J, Falagán Martínez S, Sánchez Martínez R, Casado E, Ramírez de Molina A, Sereno M. Merino Salvador M, et al. Crit Rev Oncol Hematol. 2017 Apr;112:31-40. doi: 10.1016/j.critrevonc.2017.02.001. Epub 2017 Feb 13. Crit Rev Oncol Hematol. 2017. PMID: 28325263 Review.
79 results