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Lights and shadows of proteomic technologies for the study of protein species including isoforms, splicing variants and protein post-translational modifications.
Casado-Vela J, Cebrián A, Gómez del Pulgar MT, Sánchez-López E, Vilaseca M, Menchén L, Diema C, Sellés-Marchart S, Martínez-Esteso MJ, Yubero N, Bru-Martínez R, Lacal JC. Casado-Vela J, et al. Proteomics. 2011 Feb;11(4):590-603. doi: 10.1002/pmic.201000287. Epub 2011 Jan 13. Proteomics. 2011. PMID: 21229583 Review.
Choline Uptake and Metabolism Modulate Macrophage IL-1β and IL-18 Production.
Sanchez-Lopez E, Zhong Z, Stubelius A, Sweeney SR, Booshehri LM, Antonucci L, Liu-Bryan R, Lodi A, Terkeltaub R, Lacal JC, Murphy AN, Hoffman HM, Tiziani S, Guma M, Karin M. Sanchez-Lopez E, et al. Cell Metab. 2019 Jun 4;29(6):1350-1362.e7. doi: 10.1016/j.cmet.2019.03.011. Epub 2019 Apr 11. Cell Metab. 2019. PMID: 30982734 Free PMC article.
Choline kinase inhibition in rheumatoid arthritis.
Guma M, Sanchez-Lopez E, Lodi A, Garcia-Carbonell R, Tiziani S, Karin M, Lacal JC, Firestein GS. Guma M, et al. Ann Rheum Dis. 2015 Jul;74(7):1399-407. doi: 10.1136/annrheumdis-2014-205696. Epub 2014 Oct 1. Ann Rheum Dis. 2015. PMID: 25274633 Free PMC article.
New mitochondrial DNA synthesis enables NLRP3 inflammasome activation.
Zhong Z, Liang S, Sanchez-Lopez E, He F, Shalapour S, Lin XJ, Wong J, Ding S, Seki E, Schnabl B, Hevener AL, Greenberg HB, Kisseleva T, Karin M. Zhong Z, et al. Nature. 2018 Aug;560(7717):198-203. doi: 10.1038/s41586-018-0372-z. Epub 2018 Jul 25. Nature. 2018. PMID: 30046112 Free PMC article.
212 results