Sánchez-García L - Search Results

1

GSDMD-dependent pyroptotic induction by a multivalent CXCR4-targeted nanotoxin blocks colorectal cancer metastases.

Sala R, Rioja-Blanco E, Serna N, Sánchez-García L, Álamo P, Alba-Castellón L, Casanova I, López-Pousa A, Unzueta U, Céspedes MV, Vázquez E, Villaverde A, Mangues R. Sala R, et al. Drug Deliv. 2022 Dec;29(1):1384-1397. doi: 10.1080/10717544.2022.2069302. Drug Deliv. 2022. PMID: 35532120 Free PMC article.

2

Self-assembling toxin-based nanoparticles as self-delivered antitumoral drugs.

Sánchez-García L, Serna N, Álamo P, Sala R, Céspedes MV, Roldan M, Sánchez-Chardi A, Unzueta U, Casanova I, Mangues R, Vázquez E, Villaverde A. Sánchez-García L, et al. J Control Release. 2018 Mar 28;274:81-92. doi: 10.1016/j.jconrel.2018.01.031. Epub 2018 Jan 31. J Control Release. 2018. PMID: 29408658

3

Selective CXCR4⁺ Cancer Cell Targeting and Potent Antineoplastic Effect by a Nanostructured Version of Recombinant Ricin.

Díaz R, Pallarès V, Cano-Garrido O, Serna N, Sánchez-García L, Falgàs A, Pesarrodona M, Unzueta U, Sánchez-Chardi A, Sánchez JM, Casanova I, Vázquez E, Mangues R, Villaverde A. Díaz R, et al. Small. 2018 Jun;14(26):e1800665. doi: 10.1002/smll.201800665. Epub 2018 May 29. Small. 2018. PMID: 29845742

4

Collaborative membrane activity and receptor-dependent tumor cell targeting for precise nanoparticle delivery in CXCR4⁺ colorectal cancer.

Sala R, Sánchez-García L, Serna N, Céspedes MV, Casanova I, Roldán M, Sánchez-Chardi A, Unzueta U, Vázquez E, Mangues R, Villaverde A. Sala R, et al. Acta Biomater. 2019 Nov;99:426-432. doi: 10.1016/j.actbio.2019.09.002. Epub 2019 Sep 5. Acta Biomater. 2019. PMID: 31494293

5

Engineering Secretory Amyloids for Remote and Highly Selective Destruction of Metastatic Foci.

Céspedes MV, Cano-Garrido O, Álamo P, Sala R, Gallardo A, Serna N, Falgàs A, Voltà-Durán E, Casanova I, Sánchez-Chardi A, López-Laguna H, Sánchez-García L, Sánchez JM, Unzueta U, Vázquez E, Mangues R, Villaverde A. Céspedes MV, et al. Adv Mater. 2020 Feb;32(7):e1907348. doi: 10.1002/adma.201907348. Epub 2019 Dec 27. Adv Mater. 2020. PMID: 31879981

6

Nanostructured toxins for the selective destruction of drug-resistant human CXCR4⁺ colorectal cancer stem cells.

Serna N, Álamo P, Ramesh P, Vinokurova D, Sánchez-García L, Unzueta U, Gallardo A, Céspedes MV, Vázquez E, Villaverde A, Mangues R, Medema JP. Serna N, et al. J Control Release. 2020 Apr 10;320:96-104. doi: 10.1016/j.jconrel.2020.01.019. Epub 2020 Jan 10. J Control Release. 2020. PMID: 31931052

7

An Auristatin nanoconjugate targeting CXCR4+ leukemic cells blocks acute myeloid leukemia dissemination.

Pallarès V, Unzueta U, Falgàs A, Sánchez-García L, Serna N, Gallardo A, Morris GA, Alba-Castellón L, Álamo P, Sierra J, Villaverde A, Vázquez E, Casanova I, Mangues R. Pallarès V, et al. J Hematol Oncol. 2020 Apr 15;13(1):36. doi: 10.1186/s13045-020-00863-9. J Hematol Oncol. 2020. PMID: 32295630 Free PMC article.

8

Selective delivery of T22-PE24-H6 to CXCR4⁺ diffuse large B-cell lymphoma cells leads to wide therapeutic index in a disseminated mouse model.

Falgàs A, Pallarès V, Serna N, Sánchez-García L, Sierra J, Gallardo A, Alba-Castellón L, Álamo P, Unzueta U, Villaverde A, Vázquez E, Mangues R, Casanova I. Falgàs A, et al. Theranostics. 2020 Apr 6;10(12):5169-5180. doi: 10.7150/thno.43231. eCollection 2020. Theranostics. 2020. PMID: 32373205 Free PMC article.

9

Antineoplastic effect of a diphtheria toxin-based nanoparticle targeting acute myeloid leukemia cells overexpressing CXCR4.

Pallarès V, Núñez Y, Sánchez-García L, Falgàs A, Serna N, Unzueta U, Gallardo A, Alba-Castellón L, Álamo P, Sierra J, Villaverde A, Vázquez E, Casanova I, Mangues R. Pallarès V, et al. J Control Release. 2021 Jul 10;335:117-129. doi: 10.1016/j.jconrel.2021.05.014. Epub 2021 May 15. J Control Release. 2021. PMID: 34004204

10

CXCR4-targeted nanotoxins induce GSDME-dependent pyroptosis in head and neck squamous cell carcinoma.

Rioja-Blanco E, Arroyo-Solera I, Álamo P, Casanova I, Gallardo A, Unzueta U, Serna N, Sánchez-García L, Quer M, Villaverde A, Vázquez E, León X, Alba-Castellón L, Mangues R. Rioja-Blanco E, et al. J Exp Clin Cancer Res. 2022 Feb 4;41(1):49. doi: 10.1186/s13046-022-02267-8. J Exp Clin Cancer Res. 2022. PMID: 35120582 Free PMC article.

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