Ryu S - Search Results

1

Mapping the Degradable Kinome Provides a Resource for Expedited Degrader Development.

Donovan KA, Ferguson FM, Bushman JW, Eleuteri NA, Bhunia D, Ryu S, Tan L, Shi K, Yue H, Liu X, Dobrovolsky D, Jiang B, Wang J, Hao M, You I, Teng M, Liang Y, Hatcher J, Li Z, Manz TD, Groendyke B, Hu W, Nam Y, Sengupta S, Cho H, Shin I, Agius MP, Ghobrial IM, Ma MW, Che J, Buhrlage SJ, Sim T, Gray NS, Fischer ES. Donovan KA, et al. Among authors: ryu s. Cell. 2020 Dec 10;183(6):1714-1731.e10. doi: 10.1016/j.cell.2020.10.038. Epub 2020 Dec 3. Cell. 2020. PMID: 33275901 Free PMC article.

2

Two-photon probes for the endoplasmic reticulum: its detection in a live tissue by two-photon microscopy.

Choi JW , Choi SH , Hong ST , Kim MS , Ryu SS , Yoon YU , Paik KC , Han MS , Sim T , Cho BR . Choi JW , et al. Chem Commun (Camb). 2020 Mar 28;56(25):3657-3660. doi: 10.1039/d0cc00236d. Epub 2020 Feb 28. Chem Commun (Camb). 2020. PMID: 32108200

3

Anti-glioma effects of 2-aminothiophene-3-carboxamide derivatives, ANO1 channel blockers.

Choi SH, Ryu S, Sim K, Song C, Shin I, Kim SS, Lee YS, Park JY, Sim T. Choi SH, et al. Among authors: ryu s. Eur J Med Chem. 2020 Dec 15;208:112688. doi: 10.1016/j.ejmech.2020.112688. Epub 2020 Aug 8. Eur J Med Chem. 2020. PMID: 32906067

4

Novel and Potent Small Molecules against Melanoma Harboring BRAF Class I/II/III Mutants for Overcoming Drug Resistance.

Kim N, Shin I, Lee J, Jeon E, Kim Y, Ryu S, Ju E, Cho W, Sim T. Kim N, et al. Among authors: ryu s. Int J Mol Sci. 2021 Apr 6;22(7):3783. doi: 10.3390/ijms22073783. Int J Mol Sci. 2021. PMID: 33917428 Free PMC article.

5

Identification of Thieno[3,2-d]pyrimidine Derivatives as Dual Inhibitors of Focal Adhesion Kinase and FMS-like Tyrosine Kinase 3.

Cho H, Shin I, Yoon H, Jeon E, Lee J, Kim Y, Ryu S, Song C, Kwon NH, Moon Y, Kim S, Kim ND, Choi HG, Sim T. Cho H, et al. Among authors: ryu s. J Med Chem. 2021 Aug 26;64(16):11934-11957. doi: 10.1021/acs.jmedchem.1c00459. Epub 2021 Jul 29. J Med Chem. 2021. PMID: 34324343

6

Anti-cancer effects of 3,4-dihydropyrimido[4,5-d]pyrimidin-2(1H)-one derivatives on hepatocellular carcinoma harboring FGFR4 activation.

Nam Y, Shin I, Kim Y, Ryu S, Kim N, Ju E, Sim T. Nam Y, et al. Among authors: ryu s. Neoplasia. 2022 Jan;24(1):34-49. doi: 10.1016/j.neo.2021.11.011. Epub 2021 Dec 3. Neoplasia. 2022. PMID: 34864570 Free PMC article.

7

Novel Small Molecules Capable of Blocking mtRAS-Signaling Pathway.

Kim N, Shin I, Kim Y, Jeon E, Lee J, Lee C, Nam Y, Lee S, Ju E, Kim C, Son W, Ryu S, Ko M, Sim T. Kim N, et al. Among authors: ryu s. Front Oncol. 2021 Dec 9;11:768022. doi: 10.3389/fonc.2021.768022. eCollection 2021. Front Oncol. 2021. PMID: 34956887 Free PMC article.

8

Novel Macrocyclic Peptidomimetics Targeting the Polo-Box Domain of Polo-Like Kinase 1.

Ryu S, Park JE, Ham YJ, Lim DC, Kwiatkowski NP, Kim DH, Bhunia D, Kim ND, Yaffe MB, Son W, Kim N, Choi TI, Swain P, Kim CH, Lee JY, Gray NS, Lee KS, Sim T. Ryu S, et al. J Med Chem. 2022 Feb 10;65(3):1915-1932. doi: 10.1021/acs.jmedchem.1c01359. Epub 2022 Jan 14. J Med Chem. 2022. PMID: 35029981 Free PMC article.

9

Identification of Pyridinyltriazine Derivatives as Potent panFGFR Inhibitors against Gatekeeper Mutants for Overcoming Drug Resistance.

Ryu S, Nam Y, Kim N, Shin I, Jeon E, Kim Y, Kim ND, Sim T. Ryu S, et al. J Med Chem. 2022 Apr 28;65(8):6017-6038. doi: 10.1021/acs.jmedchem.1c01776. Epub 2022 Apr 18. J Med Chem. 2022. PMID: 35436119

10

Identification of Thiazolo[5,4-b]pyridine Derivatives as c-KIT Inhibitors for Overcoming Imatinib Resistance.

Nam Y, Kim C, Han J, Ryu S, Cho H, Song C, Kim ND, Kim N, Sim T. Nam Y, et al. Among authors: ryu s. Cancers (Basel). 2022 Dec 26;15(1):143. doi: 10.3390/cancers15010143. Cancers (Basel). 2022. PMID: 36612139 Free PMC article.

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