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Pin1-mediated Runx2 modification is critical for skeletal development.
Yoon WJ, Islam R, Cho YD, Woo KM, Baek JH, Uchida T, Komori T, van Wijnen A, Stein JL, Lian JB, Stein GS, Choi JY, Bae SC, Ryoo HM. Yoon WJ, et al. Among authors: ryoo hm. J Cell Physiol. 2013 Dec;228(12):2377-85. doi: 10.1002/jcp.24403. J Cell Physiol. 2013. PMID: 23702614 Free PMC article.
Transient upregulation of CBFA1 in response to bone morphogenetic protein-2 and transforming growth factor beta1 in C2C12 myogenic cells coincides with suppression of the myogenic phenotype but is not sufficient for osteoblast differentiation.
Lee MH, Javed A, Kim HJ, Shin HI, Gutierrez S, Choi JY, Rosen V, Stein JL, van Wijnen AJ, Stein GS, Lian JB, Ryoo HM. Lee MH, et al. Among authors: ryoo hm. J Cell Biochem. 1999 Apr 1;73(1):114-25. J Cell Biochem. 1999. PMID: 10088730
Runx2 is a common target of transforming growth factor beta1 and bone morphogenetic protein 2, and cooperation between Runx2 and Smad5 induces osteoblast-specific gene expression in the pluripotent mesenchymal precursor cell line C2C12.
Lee KS, Kim HJ, Li QL, Chi XZ, Ueta C, Komori T, Wozney JM, Kim EG, Choi JY, Ryoo HM, Bae SC. Lee KS, et al. Among authors: ryoo hm. Mol Cell Biol. 2000 Dec;20(23):8783-92. doi: 10.1128/MCB.20.23.8783-8792.2000. Mol Cell Biol. 2000. PMID: 11073979 Free PMC article.
245 results