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Potential Binding Sites of Pharmacological Chaperone NCGC00241607 on Mutant β-Glucocerebrosidase and Its Efficacy on Patient-Derived Cell Cultures in Gaucher and Parkinson's Disease.
Kopytova AE, Rychkov GN, Cheblokov AA, Grigor'eva EV, Nikolaev MA, Yarkova ES, Sorogina DA, Ibatullin FM, Baydakova GV, Izyumchenko AD, Bogdanova DA, Boitsov VM, Rybakov AV, Miliukhina IV, Bezrukikh VA, Salogub GN, Zakharova EY, Pchelina SN, Emelyanov AK. Kopytova AE, et al. Among authors: rychkov gn. Int J Mol Sci. 2023 May 22;24(10):9105. doi: 10.3390/ijms24109105. Int J Mol Sci. 2023. PMID: 37240451 Free PMC article.
Ambroxol increases glucocerebrosidase (GCase) activity and restores GCase translocation in primary patient-derived macrophages in Gaucher disease and Parkinsonism.
Kopytova AE, Rychkov GN, Nikolaev MA, Baydakova GV, Cheblokov AA, Senkevich KA, Bogdanova DA, Bolshakova OI, Miliukhina IV, Bezrukikh VA, Salogub GN, Sarantseva SV, Usenko TC, Zakharova EY, Emelyanov AK, Pchelina SN. Kopytova AE, et al. Among authors: rychkov gn. Parkinsonism Relat Disord. 2021 Mar;84:112-121. doi: 10.1016/j.parkreldis.2021.02.003. Epub 2021 Feb 10. Parkinsonism Relat Disord. 2021. PMID: 33609962
Partially Assembled Nucleosome Structures at Atomic Detail.
Rychkov GN, Ilatovskiy AV, Nazarov IB, Shvetsov AV, Lebedev DV, Konev AY, Isaev-Ivanov VV, Onufriev AV. Rychkov GN, et al. Biophys J. 2017 Feb 7;112(3):460-472. doi: 10.1016/j.bpj.2016.10.041. Epub 2016 Dec 28. Biophys J. 2017. PMID: 28038734 Free PMC article.
[Knotted proteins].
Stepanenko OV, Bublikov GS, Stepanenko OV, Rychkov GN, Povarova OI, Verkhusha VV, Turoverov KK, Kuznetsova IM. Stepanenko OV, et al. Among authors: rychkov gn. Tsitologiia. 2015;57(3):177-83. Tsitologiia. 2015. PMID: 26021166 Review. Russian.
12 results