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An atlas of substrate specificities for the human serine/threonine kinome.
Johnson JL, Yaron TM, Huntsman EM, Kerelsky A, Song J, Regev A, Lin TY, Liberatore K, Cizin DM, Cohen BM, Vasan N, Ma Y, Krismer K, Robles JT, van de Kooij B, van Vlimmeren AE, Andrée-Busch N, Käufer NF, Dorovkov MV, Ryazanov AG, Takagi Y, Kastenhuber ER, Goncalves MD, Hopkins BD, Elemento O, Taatjes DJ, Maucuer A, Yamashita A, Degterev A, Uduman M, Lu J, Landry SD, Zhang B, Cossentino I, Linding R, Blenis J, Hornbeck PV, Turk BE, Yaffe MB, Cantley LC. Johnson JL, et al. Among authors: ryazanov ag. Nature. 2023 Jan;613(7945):759-766. doi: 10.1038/s41586-022-05575-3. Epub 2023 Jan 11. Nature. 2023. PMID: 36631611 Free PMC article.
Transcriptional-translational conflict is a barrier to cellular transformation and cancer progression.
Jana S, Brahma S, Arora S, Wladyka CL, Hoang P, Blinka S, Hough R, Horn JL, Liu Y, Wang LJ, Depeille P, Smith E, Montgomery RB, Lee JK, Haffner MC, Vakar-Lopez F, Grivas P, Wright JL, Lam HM, Black PC, Roose JP, Ryazanov AG, Subramaniam AR, Henikoff S, Hsieh AC. Jana S, et al. Among authors: ryazanov ag. Cancer Cell. 2023 May 8;41(5):853-870.e13. doi: 10.1016/j.ccell.2023.03.021. Epub 2023 Apr 20. Cancer Cell. 2023. PMID: 37084735 Free PMC article.
TRPM7 deficiency exacerbates cardiovascular and renal damage induced by aldosterone-salt.
Rios FJ, Zou ZG, Harvey AP, Harvey KY, Camargo LL, Neves KB, Nichol SEF, Alves-Lopes R, Cheah A, Zahraa M, Ryazanov AG, Ryazanova L, Gudermann T, Chubanov V, Montezano AC, Touyz RM. Rios FJ, et al. Among authors: ryazanov ag. Commun Biol. 2022 Jul 26;5(1):746. doi: 10.1038/s42003-022-03715-z. Commun Biol. 2022. PMID: 35882956 Free PMC article.
Chanzyme TRPM7 protects against cardiovascular inflammation and fibrosis.
Rios FJ, Zou ZG, Harvey AP, Harvey KY, Nosalski R, Anyfanti P, Camargo LL, Lacchini S, Ryazanov AG, Ryazanova L, McGrath S, Guzik TJ, Goodyear CS, Montezano AC, Touyz RM. Rios FJ, et al. Among authors: ryazanov ag. Cardiovasc Res. 2020 Mar 1;116(3):721-735. doi: 10.1093/cvr/cvz164. Cardiovasc Res. 2020. PMID: 31250885 Free PMC article.
Glycine supplementation extends lifespan of male and female mice.
Miller RA, Harrison DE, Astle CM, Bogue MA, Brind J, Fernandez E, Flurkey K, Javors M, Ladiges W, Leeuwenburgh C, Macchiarini F, Nelson J, Ryazanov AG, Snyder J, Stearns TM, Vaughan DE, Strong R. Miller RA, et al. Among authors: ryazanov ag. Aging Cell. 2019 Jun;18(3):e12953. doi: 10.1111/acel.12953. Epub 2019 Mar 27. Aging Cell. 2019. PMID: 30916479 Free PMC article.
69 results