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Perturbations in RhoA signalling cause altered migration and impaired neuritogenesis in human iPSC-derived neural cells with PARK2 mutation.
Bogetofte H, Jensen P, Okarmus J, Schmidt SI, Agger M, Ryding M, Nørregaard P, Fenger C, Zeng X, Graakjær J, Ryan BJ, Wade-Martins R, Larsen MR, Meyer M. Bogetofte H, et al. Among authors: ryan bj. Neurobiol Dis. 2019 Dec;132:104581. doi: 10.1016/j.nbd.2019.104581. Epub 2019 Aug 21. Neurobiol Dis. 2019. PMID: 31445161 Free article.
Deficits in dopaminergic transmission precede neuron loss and dysfunction in a new Parkinson model.
Janezic S, Threlfell S, Dodson PD, Dowie MJ, Taylor TN, Potgieter D, Parkkinen L, Senior SL, Anwar S, Ryan B, Deltheil T, Kosillo P, Cioroch M, Wagner K, Ansorge O, Bannerman DM, Bolam JP, Magill PJ, Cragg SJ, Wade-Martins R. Janezic S, et al. Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):E4016-25. doi: 10.1073/pnas.1309143110. Epub 2013 Sep 30. Proc Natl Acad Sci U S A. 2013. PMID: 24082145 Free PMC article.
Region-specific deficits in dopamine, but not norepinephrine, signaling in a novel A30P α-synuclein BAC transgenic mouse.
Taylor TN, Potgieter D, Anwar S, Senior SL, Janezic S, Threlfell S, Ryan B, Parkkinen L, Deltheil T, Cioroch M, Livieratos A, Oliver PL, Jennings KA, Davies KE, Ansorge O, Bannerman DM, Cragg SJ, Wade-Martins R. Taylor TN, et al. Neurobiol Dis. 2014 Feb;62:193-207. doi: 10.1016/j.nbd.2013.10.005. Epub 2013 Oct 10. Neurobiol Dis. 2014. PMID: 24121116 Free PMC article.
ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons.
Fernandes HJ, Hartfield EM, Christian HC, Emmanoulidou E, Zheng Y, Booth H, Bogetofte H, Lang C, Ryan BJ, Sardi SP, Badger J, Vowles J, Evetts S, Tofaris GK, Vekrellis K, Talbot K, Hu MT, James W, Cowley SA, Wade-Martins R. Fernandes HJ, et al. Among authors: ryan bj. Stem Cell Reports. 2016 Mar 8;6(3):342-56. doi: 10.1016/j.stemcr.2016.01.013. Epub 2016 Feb 18. Stem Cell Reports. 2016. PMID: 26905200 Free PMC article.
A novel role for endothelial tetrahydrobiopterin in mitochondrial redox balance.
Bailey J, Shaw A, Fischer R, Ryan BJ, Kessler BM, McCullagh J, Wade-Martins R, Channon KM, Crabtree MJ. Bailey J, et al. Among authors: ryan bj. Free Radic Biol Med. 2017 Mar;104:214-225. doi: 10.1016/j.freeradbiomed.2017.01.012. Epub 2017 Jan 17. Free Radic Biol Med. 2017. PMID: 28104455 Free PMC article.
150 results