Ruzinova MB - Search Results

1

IRAK4 Signaling Drives Resistance to Checkpoint Immunotherapy in Pancreatic Ductal Adenocarcinoma.

Somani VK, Zhang D, Dodhiawala PB, Lander VE, Liu X, Kang LI, Chen HP, Knolhoff BL, Li L, Grierson PM, Ruzinova MB, DeNardo DG, Lim KH. Somani VK, et al. Among authors: ruzinova mb. Gastroenterology. 2022 Jun;162(7):2047-2062. doi: 10.1053/j.gastro.2022.02.035. Epub 2022 Mar 7. Gastroenterology. 2022. PMID: 35271824 Free PMC article.

2

Constitutive IRAK4 Activation Underlies Poor Prognosis and Chemoresistance in Pancreatic Ductal Adenocarcinoma.

Zhang D, Li L, Jiang H, Knolhoff BL, Lockhart AC, Wang-Gillam A, DeNardo DG, Ruzinova MB, Lim KH. Zhang D, et al. Among authors: ruzinova mb. Clin Cancer Res. 2017 Apr 1;23(7):1748-1759. doi: 10.1158/1078-0432.CCR-16-1121. Epub 2016 Oct 4. Clin Cancer Res. 2017. PMID: 27702822 Free PMC article.

3

Utility of a multidisciplinary tumor board in the management of pancreatic and upper gastrointestinal diseases: an observational study.

Brauer DG, Strand MS, Sanford DE, Kushnir VM, Lim KH, Mullady DK, Tan BR Jr, Wang-Gillam A, Morton AE, Ruzinova MB, Parikh PJ, Narra VR, Fowler KJ, Doyle MB, Chapman WC, Strasberg SS, Hawkins WG, Fields RC. Brauer DG, et al. Among authors: ruzinova mb. HPB (Oxford). 2017 Feb;19(2):133-139. doi: 10.1016/j.hpb.2016.11.002. Epub 2016 Dec 1. HPB (Oxford). 2017. PMID: 27916436 Free PMC article.

4

Tumor-Stroma IL1β-IRAK4 Feedforward Circuitry Drives Tumor Fibrosis, Chemoresistance, and Poor Prognosis in Pancreatic Cancer.

Zhang D, Li L, Jiang H, Li Q, Wang-Gillam A, Yu J, Head R, Liu J, Ruzinova MB, Lim KH. Zhang D, et al. Among authors: ruzinova mb. Cancer Res. 2018 Apr 1;78(7):1700-1712. doi: 10.1158/0008-5472.CAN-17-1366. Epub 2018 Jan 23. Cancer Res. 2018. PMID: 29363544 Free PMC article.

5

Distinct clinical and magnetic resonance features of metastatic hepatocellular carcinoma treated with pembrolizumab: A case report of late response after pseudoprogression.

Grierson P, Crites D, Ruzinova MB, Yano M, Lim KH. Grierson P, et al. Among authors: ruzinova mb. Hepatol Commun. 2017 Dec 19;2(2):148-151. doi: 10.1002/hep4.1132. eCollection 2018 Feb. Hepatol Commun. 2017. PMID: 29404522 Free PMC article.

6

IRAK4 mediates colitis-induced tumorigenesis and chemoresistance in colorectal cancer.

Li Q, Chen Y, Zhang D, Grossman J, Li L, Khurana N, Jiang H, Grierson PM, Herndon J, DeNardo DG, Challen GA, Liu J, Ruzinova MB, Fields RC, Lim KH. Li Q, et al. Among authors: ruzinova mb. JCI Insight. 2019 Oct 3;4(19):e130867. doi: 10.1172/jci.insight.130867. JCI Insight. 2019. PMID: 31527315 Free PMC article.

7

CC Chemokine Receptor 2-Targeting Copper Nanoparticles for Positron Emission Tomography-Guided Delivery of Gemcitabine for Pancreatic Ductal Adenocarcinoma.

Zhang X, Detering L, Sultan D, Luehmann H, Li L, Heo GS, Zhang X, Lou L, Grierson PM, Greco S, Ruzinova M, Laforest R, Dehdashti F, Lim KH, Liu Y. Zhang X, et al. ACS Nano. 2021 Jan 26;15(1):1186-1198. doi: 10.1021/acsnano.0c08185. Epub 2021 Jan 6. ACS Nano. 2021. PMID: 33406361 Free PMC article.

8

The MK2/Hsp27 axis is a major survival mechanism for pancreatic ductal adenocarcinoma under genotoxic stress.

Grierson PM, Dodhiawala PB, Cheng Y, Chen TH, Khawar IA, Wei Q, Zhang D, Li L, Herndon J, Monahan JB, Ruzinova MB, Lim KH. Grierson PM, et al. Among authors: ruzinova mb. Sci Transl Med. 2021 Dec;13(622):eabb5445. doi: 10.1126/scitranslmed.abb5445. Epub 2021 Dec 1. Sci Transl Med. 2021. PMID: 34851698 Free PMC article.

9

DUSP6 mediates resistance to JAK2 inhibition and drives leukemic progression.

Kong T, Laranjeira ABA, Yang K, Fisher DAC, Yu L, Poittevin De La Frégonnière L, Wang AZ, Ruzinova MB, Fowles JS, Fulbright MC, Cox MJ, Celik H, Challen GA, Huang S, Oh ST. Kong T, et al. Among authors: ruzinova mb. Nat Cancer. 2023 Jan;4(1):108-127. doi: 10.1038/s43018-022-00486-8. Epub 2022 Dec 29. Nat Cancer. 2023. PMID: 36581736

10

Perioperative Therapy for Surgically Resectable Pancreatic Adenocarcinoma.

Du L, DeFoe M, Ruzinova MB, Olsen JR, Wang-Gillam A. Du L, et al. Among authors: ruzinova mb. Hematol Oncol Clin North Am. 2015 Aug;29(4):717-26. doi: 10.1016/j.hoc.2015.04.011. Epub 2015 May 30. Hematol Oncol Clin North Am. 2015. PMID: 26226906 Free PMC article. Review.

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