Rutledge AC - Search Results

1

Fructose: a highly lipogenic nutrient implicated in insulin resistance, hepatic steatosis, and the metabolic syndrome.

Dekker MJ, Su Q, Baker C, Rutledge AC, Adeli K. Dekker MJ, et al. Among authors: rutledge ac. Am J Physiol Endocrinol Metab. 2010 Nov;299(5):E685-94. doi: 10.1152/ajpendo.00283.2010. Epub 2010 Sep 7. Am J Physiol Endocrinol Metab. 2010. PMID: 20823452 Free article. Review.

2

Mechanisms of glucosamine-induced suppression of the hepatic assembly and secretion of apolipoprotein B-100-containing lipoproteins.

Qiu W, Avramoglu RK, Rutledge AC, Tsai J, Adeli K. Qiu W, et al. Among authors: rutledge ac. J Lipid Res. 2006 Aug;47(8):1749-61. doi: 10.1194/jlr.M500363-JLR200. Epub 2006 May 3. J Lipid Res. 2006. PMID: 16672736 Free article.

3

Fructose and the metabolic syndrome: pathophysiology and molecular mechanisms.

Rutledge AC, Adeli K. Rutledge AC, et al. Nutr Rev. 2007 Jun;65(6 Pt 2):S13-23. doi: 10.1111/j.1753-4887.2007.tb00322.x. Nutr Rev. 2007. PMID: 17605309 Review.

4

Mechanisms targeting apolipoprotein B100 to proteasomal degradation: evidence that degradation is initiated by BiP binding at the N terminus and the formation of a p97 complex at the C terminus.

Rutledge AC, Qiu W, Zhang R, Kohen-Avramoglu R, Nemat-Gorgani N, Adeli K. Rutledge AC, et al. Arterioscler Thromb Vasc Biol. 2009 Apr;29(4):579-85. doi: 10.1161/ATVBAHA.108.181859. Epub 2009 Jan 22. Arterioscler Thromb Vasc Biol. 2009. PMID: 19164805

5

Glucosamine-induced endoplasmic reticulum stress attenuates apolipoprotein B100 synthesis via PERK signaling.

Qiu W, Su Q, Rutledge AC, Zhang J, Adeli K. Qiu W, et al. Among authors: rutledge ac. J Lipid Res. 2009 Sep;50(9):1814-23. doi: 10.1194/jlr.M800343-JLR200. Epub 2009 Apr 21. J Lipid Res. 2009. PMID: 19383982 Free PMC article.

6

Apolipoprotein B100 biogenesis: a complex array of intracellular mechanisms regulating folding, stability, and lipoprotein assembly.

Rutledge AC, Su Q, Adeli K. Rutledge AC, et al. Biochem Cell Biol. 2010 Apr;88(2):251-67. doi: 10.1139/o09-168. Biochem Cell Biol. 2010. PMID: 20453928 Review.

7

Role of cysteine-protease CGHC motifs of ER-60, a protein disulfide isomerase, in hepatic apolipoprotein B100 degradation.

Rutledge AC, Qiu W, Zhang R, Urade R, Adeli K. Rutledge AC, et al. Arch Biochem Biophys. 2013 Sep 1;537(1):104-12. doi: 10.1016/j.abb.2013.06.013. Epub 2013 Jul 1. Arch Biochem Biophys. 2013. PMID: 23827315

8

Activation of the dsRNA-Activated Protein Kinase PKR in Mitochondrial Dysfunction and Inflammatory Stress in Metabolic Syndrome.

Sud N, Rutledge AC, Pan K, Su Q. Sud N, et al. Among authors: rutledge ac. Curr Pharm Des. 2016;22(18):2697-703. doi: 10.2174/1381612822666160202141845. Curr Pharm Des. 2016. PMID: 26831644 Review.

9

Inhibition of mitochondrial translation as a therapeutic strategy for human acute myeloid leukemia.

Skrtić M, Sriskanthadevan S, Jhas B, Gebbia M, Wang X, Wang Z, Hurren R, Jitkova Y, Gronda M, Maclean N, Lai CK, Eberhard Y, Bartoszko J, Spagnuolo P, Rutledge AC, Datti A, Ketela T, Moffat J, Robinson BH, Cameron JH, Wrana J, Eaves CJ, Minden MD, Wang JC, Dick JE, Humphries K, Nislow C, Giaever G, Schimmer AD. Skrtić M, et al. Among authors: rutledge ac. Cancer Cell. 2011 Nov 15;20(5):674-88. doi: 10.1016/j.ccr.2011.10.015. Cancer Cell. 2011. PMID: 22094260 Free PMC article.

10

Lysosomal disruption preferentially targets acute myeloid leukemia cells and progenitors.

Sukhai MA, Prabha S, Hurren R, Rutledge AC, Lee AY, Sriskanthadevan S, Sun H, Wang X, Skrtic M, Seneviratne A, Cusimano M, Jhas B, Gronda M, MacLean N, Cho EE, Spagnuolo PA, Sharmeen S, Gebbia M, Urbanus M, Eppert K, Dissanayake D, Jonet A, Dassonville-Klimpt A, Li X, Datti A, Ohashi PS, Wrana J, Rogers I, Sonnet P, Ellis WY, Corey SJ, Eaves C, Minden MD, Wang JC, Dick JE, Nislow C, Giaever G, Schimmer AD. Sukhai MA, et al. Among authors: rutledge ac. J Clin Invest. 2013 Jan;123(1):315-28. doi: 10.1172/JCI64180. Epub 2012 Dec 3. J Clin Invest. 2013. PMID: 23202731 Free PMC article. Clinical Trial.

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