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Release of IFNγ by Acute Myeloid Leukemia Cells Remodels Bone Marrow Immune Microenvironment by Inducing Regulatory T Cells.
Corradi G, Bassani B, Simonetti G, Sangaletti S, Vadakekolathu J, Fontana MC, Pazzaglia M, Gulino A, Tripodo C, Cristiano G, Bandini L, Ottaviani E, Ocadlikova D, Piccioli M, Martinelli G, Colombo MP, Rutella S, Cavo M, Ciciarello M, Curti A. Corradi G, et al. Among authors: rutella s. Clin Cancer Res. 2022 Jul 15;28(14):3141-3155. doi: 10.1158/1078-0432.CCR-21-3594. Clin Cancer Res. 2022. PMID: 35349670
Modulation of tryptophan catabolism by human leukemic cells results in the conversion of CD25- into CD25+ T regulatory cells.
Curti A, Pandolfi S, Valzasina B, Aluigi M, Isidori A, Ferri E, Salvestrini V, Bonanno G, Rutella S, Durelli I, Horenstein AL, Fiore F, Massaia M, Colombo MP, Baccarani M, Lemoli RM. Curti A, et al. Among authors: rutella s. Blood. 2007 Apr 1;109(7):2871-7. doi: 10.1182/blood-2006-07-036863. Blood. 2007. PMID: 17164341 Free article.
Indoleamine 2,3-dioxygenase-expressing leukemic dendritic cells impair a leukemia-specific immune response by inducing potent T regulatory cells.
Curti A, Trabanelli S, Onofri C, Aluigi M, Salvestrini V, Ocadlikova D, Evangelisti C, Rutella S, De Cristofaro R, Ottaviani E, Baccarani M, Lemoli RM. Curti A, et al. Among authors: rutella s. Haematologica. 2010 Dec;95(12):2022-30. doi: 10.3324/haematol.2010.025924. Epub 2010 Aug 26. Haematologica. 2010. PMID: 20801903 Free PMC article.
Indoleamine 2,3-dioxygenase 1 (IDO1) activity correlates with immune system abnormalities in multiple myeloma.
Bonanno G, Mariotti A, Procoli A, Folgiero V, Natale D, De Rosa L, Majolino I, Novarese L, Rocci A, Gambella M, Ciciarello M, Scambia G, Palumbo A, Locatelli F, De Cristofaro R, Rutella S. Bonanno G, et al. Among authors: rutella s. J Transl Med. 2012 Dec 11;10:247. doi: 10.1186/1479-5876-10-247. J Transl Med. 2012. PMID: 23232072 Free PMC article.
Immune-Phenotyping and Transcriptomic Profiling of Peripheral Blood Mononuclear Cells From Patients With Breast Cancer: Identification of a 3 Gene Signature Which Predicts Relapse of Triple Negative Breast Cancer.
Foulds GA, Vadakekolathu J, Abdel-Fatah TMA, Nagarajan D, Reeder S, Johnson C, Hood S, Moseley PM, Chan SYT, Pockley AG, Rutella S, McArdle SEB. Foulds GA, et al. Among authors: rutella s. Front Immunol. 2018 Sep 11;9:2028. doi: 10.3389/fimmu.2018.02028. eCollection 2018. Front Immunol. 2018. PMID: 30254632 Free PMC article. Clinical Trial.
Flow cytometry and targeted immune transcriptomics identify distinct profiles in patients with chronic myeloid leukemia receiving tyrosine kinase inhibitors with or without interferon-α.
Alves R, McArdle SEB, Vadakekolathu J, Gonçalves AC, Freitas-Tavares P, Pereira A, Almeida AM, Sarmento-Ribeiro AB, Rutella S. Alves R, et al. Among authors: rutella s. J Transl Med. 2020 Jan 3;18(1):2. doi: 10.1186/s12967-019-02194-x. J Transl Med. 2020. PMID: 31900171 Free PMC article.
229 results