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rA1M-035, a Physicochemically Improved Human Recombinant α1-Microglobulin, Has Therapeutic Effects in Rhabdomyolysis-Induced Acute Kidney Injury.
Åkerström B, Rosenlöf L, Hägerwall A, Rutardottir S, Ahlstedt J, Johansson ME, Erlandsson L, Allhorn M, Gram M. Åkerström B, et al. Among authors: rutardottir s. Antioxid Redox Signal. 2019 Feb 1;30(4):489-504. doi: 10.1089/ars.2017.7181. Epub 2018 Apr 11. Antioxid Redox Signal. 2019. PMID: 29471681 Free PMC article.
A1M/α1-microglobulin protects from heme-induced placental and renal damage in a pregnant sheep model of preeclampsia.
Wester-Rosenlöf L, Casslén V, Axelsson J, Edström-Hägerwall A, Gram M, Holmqvist M, Johansson ME, Larsson I, Ley D, Marsal K, Mörgelin M, Rippe B, Rutardottir S, Shohani B, Akerström B, Hansson SR. Wester-Rosenlöf L, et al. Among authors: rutardottir s. PLoS One. 2014 Jan 28;9(1):e86353. doi: 10.1371/journal.pone.0086353. eCollection 2014. PLoS One. 2014. PMID: 24489717 Free PMC article.
The heme and radical scavenger α1-microglobulin (A1M) confers early protection of the immature brain following preterm intraventricular hemorrhage.
Romantsik O, Agyemang AA, Sveinsdóttir S, Rutardóttir S, Holmqvist B, Cinthio M, Mörgelin M, Gumus G, Karlsson H, Hansson SR, Åkerström B, Ley D, Gram M. Romantsik O, et al. Among authors: rutardottir s. J Neuroinflammation. 2019 Jun 7;16(1):122. doi: 10.1186/s12974-019-1486-4. J Neuroinflammation. 2019. PMID: 31174551 Free PMC article.
Characterization of heme binding to recombinant α1-microglobulin.
Karnaukhova E, Rutardottir S, Rajabi M, Wester Rosenlöf L, Alayash AI, Åkerström B. Karnaukhova E, et al. Among authors: rutardottir s. Front Physiol. 2014 Dec 4;5:465. doi: 10.3389/fphys.2014.00465. eCollection 2014. Front Physiol. 2014. PMID: 25538624 Free PMC article.
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