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Esomeprazole covalently interacts with the cardiovascular enzyme dimethylarginine dimethylaminohydrolase: Insights into the cardiovascular risk of proton pump inhibitors.
Smith CA, Ebrahimpour A, Novikova L, Farina D, Bailey AO, Russell WK, Jain A, Saltzman AB, Malovannaya A, Prasad BVV, Hu L, Ghebre YT. Smith CA, et al. Among authors: russell wk. Biochim Biophys Acta Gen Subj. 2022 Aug;1866(8):130149. doi: 10.1016/j.bbagen.2022.130149. Epub 2022 Apr 25. Biochim Biophys Acta Gen Subj. 2022. PMID: 35472493
QTQTN motif upstream of the furin-cleavage site plays a key role in SARS-CoV-2 infection and pathogenesis.
Vu MN, Lokugamage KG, Plante JA, Scharton D, Bailey AO, Sotcheff S, Swetnam DM, Johnson BA, Schindewolf C, Alvarado RE, Crocquet-Valdes PA, Debbink K, Weaver SC, Walker DH, Russell WK, Routh AL, Plante KS, Menachery VD. Vu MN, et al. Among authors: russell wk. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2205690119. doi: 10.1073/pnas.2205690119. Epub 2022 Jul 26. Proc Natl Acad Sci U S A. 2022. PMID: 35881779 Free PMC article.
Chemically targeting the redox switch in AP1 transcription factor ΔFOSB.
Kumar A, Aglyamova G, Yim YY, Bailey AO, Lynch HM, Powell RT, Nguyen ND, Rosenthal Z, Zhao WN, Li Y, Chen J, Fan S, Lee H, Russell WK, Stephan C, Robison AJ, Haggarty SJ, Nestler EJ, Zhou J, Machius M, Rudenko G. Kumar A, et al. Among authors: russell wk. Nucleic Acids Res. 2022 Sep 9;50(16):9548-9567. doi: 10.1093/nar/gkac710. Nucleic Acids Res. 2022. PMID: 36039764 Free PMC article.
Contextual cues from cancer cells govern cancer-associated fibroblast heterogeneity.
Bota-Rabassedas N, Banerjee P, Niu Y, Cao W, Luo J, Xi Y, Tan X, Sheng K, Ahn YH, Lee S, Parra ER, Rodriguez-Canales J, Albritton J, Weiger M, Liu X, Guo HF, Yu J, Rodriguez BL, Firestone JJA, Mino B, Creighton CJ, Solis LM, Villalobos P, Raso MG, Sazer DW, Gibbons DL, Russell WK, Longmore GD, Wistuba II, Wang J, Chapman HA, Miller JS, Zong C, Kurie JM. Bota-Rabassedas N, et al. Among authors: russell wk. Cell Rep. 2021 Apr 20;35(3):109009. doi: 10.1016/j.celrep.2021.109009. Cell Rep. 2021. PMID: 33882319 Free PMC article.
PI4KIIIβ is a therapeutic target in chromosome 1q-amplified lung adenocarcinoma.
Tan X, Banerjee P, Pham EA, Rutaganira FUN, Basu K, Bota-Rabassedas N, Guo HF, Grzeskowiak CL, Liu X, Yu J, Shi L, Peng DH, Rodriguez BL, Zhang J, Zheng V, Duose DY, Solis LM, Mino B, Raso MG, Behrens C, Wistuba II, Scott KL, Smith M, Nguyen K, Lam G, Choong I, Mazumdar A, Hill JL, Gibbons DL, Brown PH, Russell WK, Shokat K, Creighton CJ, Glenn JS, Kurie JM. Tan X, et al. Among authors: russell wk. Sci Transl Med. 2020 Jan 22;12(527):eaax3772. doi: 10.1126/scitranslmed.aax3772. Sci Transl Med. 2020. PMID: 31969487 Free PMC article.
117 results