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Leukemic blasts program bone marrow adipocytes to generate a protumoral microenvironment.
Shafat MS, Oellerich T, Mohr S, Robinson SD, Edwards DR, Marlein CR, Piddock RE, Fenech M, Zaitseva L, Abdul-Aziz A, Turner J, Watkins JA, Lawes M, Bowles KM, Rushworth SA. Shafat MS, et al. Among authors: rushworth sa. Blood. 2017 Mar 9;129(10):1320-1332. doi: 10.1182/blood-2016-08-734798. Epub 2017 Jan 3. Blood. 2017. PMID: 28049638 Free article.
The bone marrow microenvironment - Home of the leukemic blasts.
Shafat MS, Gnaneswaran B, Bowles KM, Rushworth SA. Shafat MS, et al. Among authors: rushworth sa. Blood Rev. 2017 Sep;31(5):277-286. doi: 10.1016/j.blre.2017.03.004. Epub 2017 Mar 12. Blood Rev. 2017. PMID: 28318761 Review.
Acute myeloid leukemia induces protumoral p16INK4a-driven senescence in the bone marrow microenvironment.
Abdul-Aziz AM, Sun Y, Hellmich C, Marlein CR, Mistry J, Forde E, Piddock RE, Shafat MS, Morfakis A, Mehta T, Di Palma F, Macaulay I, Ingham CJ, Haestier A, Collins A, Campisi J, Bowles KM, Rushworth SA. Abdul-Aziz AM, et al. Among authors: rushworth sa. Blood. 2019 Jan 31;133(5):446-456. doi: 10.1182/blood-2018-04-845420. Epub 2018 Nov 6. Blood. 2019. PMID: 30401703 Free PMC article.
ROS-mediated PI3K activation drives mitochondrial transfer from stromal cells to hematopoietic stem cells in response to infection.
Mistry JJ, Marlein CR, Moore JA, Hellmich C, Wojtowicz EE, Smith JGW, Macaulay I, Sun Y, Morfakis A, Patterson A, Horton RH, Divekar D, Morris CJ, Haestier A, Di Palma F, Beraza N, Bowles KM, Rushworth SA. Mistry JJ, et al. Among authors: rushworth sa. Proc Natl Acad Sci U S A. 2019 Dec 3;116(49):24610-24619. doi: 10.1073/pnas.1913278116. Epub 2019 Nov 14. Proc Natl Acad Sci U S A. 2019. PMID: 31727843 Free PMC article.
Mitochondrial oxidative phosphorylation in cutaneous melanoma.
Kumar PR, Moore JA, Bowles KM, Rushworth SA, Moncrieff MD. Kumar PR, et al. Among authors: rushworth sa. Br J Cancer. 2021 Jan;124(1):115-123. doi: 10.1038/s41416-020-01159-y. Epub 2020 Nov 18. Br J Cancer. 2021. PMID: 33204029 Free PMC article. Review.
86 results