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Intratumoral injection of melatonin enhances tumor regression in cell line-derived and patient-derived xenografts of head and neck cancer by increasing mitochondrial oxidative stress.
Martinez-Ruiz L, Florido J, Rodriguez-Santana C, López-Rodríguez A, Guerra-Librero A, Fernández-Gil BI, García-Tárraga P, Garcia-Verdugo JM, Oppel F, Sudhoff H, Sánchez-Porras D, Ten-Steve A, Fernández-Martínez J, González-García P, Rusanova I, Acuña-Castroviejo D, Carriel V, Escames G. Martinez-Ruiz L, et al. Among authors: rusanova i. Biomed Pharmacother. 2023 Nov;167:115518. doi: 10.1016/j.biopha.2023.115518. Epub 2023 Sep 15. Biomed Pharmacother. 2023. PMID: 37717534 Free article.
Melatonin Targets Metabolism in Head and Neck Cancer Cells by Regulating Mitochondrial Structure and Function.
Guerra-Librero A, Fernandez-Gil BI, Florido J, Martinez-Ruiz L, Rodríguez-Santana C, Shen YQ, García-Verdugo JM, López-Rodríguez A, Rusanova I, Quiñones-Hinojosa A, Acuña-Castroviejo D, Marruecos J, De Haro T, Escames G. Guerra-Librero A, et al. Among authors: rusanova i. Antioxidants (Basel). 2021 Apr 14;10(4):603. doi: 10.3390/antiox10040603. Antioxidants (Basel). 2021. PMID: 33919790 Free PMC article.
Melatonin enhances neural stem cell differentiation and engraftment by increasing mitochondrial function.
Mendivil-Perez M, Soto-Mercado V, Guerra-Librero A, Fernandez-Gil BI, Florido J, Shen YQ, Tejada MA, Capilla-Gonzalez V, Rusanova I, Garcia-Verdugo JM, Acuña-Castroviejo D, López LC, Velez-Pardo C, Jimenez-Del-Rio M, Ferrer JM, Escames G. Mendivil-Perez M, et al. Among authors: rusanova i. J Pineal Res. 2017 Sep;63(2). doi: 10.1111/jpi.12415. Epub 2017 May 18. J Pineal Res. 2017. PMID: 28423196
Combination of melatonin and rapamycin for head and neck cancer therapy: Suppression of AKT/mTOR pathway activation, and activation of mitophagy and apoptosis via mitochondrial function regulation.
Shen YQ, Guerra-Librero A, Fernandez-Gil BI, Florido J, García-López S, Martinez-Ruiz L, Mendivil-Perez M, Soto-Mercado V, Acuña-Castroviejo D, Ortega-Arellano H, Carriel V, Diaz-Casado ME, Reiter RJ, Rusanova I, Nieto A, López LC, Escames G. Shen YQ, et al. Among authors: rusanova i. J Pineal Res. 2018 Apr;64(3). doi: 10.1111/jpi.12461. Epub 2018 Jan 9. J Pineal Res. 2018. PMID: 29247557
Protective Effects of Melatonin on the Skin: Future Perspectives.
Rusanova I, Martínez-Ruiz L, Florido J, Rodríguez-Santana C, Guerra-Librero A, Acuña-Castroviejo D, Escames G. Rusanova I, et al. Int J Mol Sci. 2019 Oct 8;20(19):4948. doi: 10.3390/ijms20194948. Int J Mol Sci. 2019. PMID: 31597233 Free PMC article. Review.
Chronodisruption and Loss of Melatonin Rhythm, Associated with Alterations in Daily Motor Activity and Mitochondrial Dynamics in Parkinsonian Zebrafish, Are Corrected by Melatonin Treatment.
Aranda-Martínez P, Fernández-Martínez J, Ramírez-Casas Y, Rodríguez-Santana C, Rusanova I, Escames G, Acuña-Castroviejo D. Aranda-Martínez P, et al. Among authors: rusanova i. Antioxidants (Basel). 2023 Apr 18;12(4):954. doi: 10.3390/antiox12040954. Antioxidants (Basel). 2023. PMID: 37107331 Free PMC article.
In Vivo Determination of Mitochondrial Respiration in 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Treated Zebrafish Reveals the Efficacy of Melatonin in Restoring Mitochondrial Normalcy.
Díaz-Casado ME, Rusanova I, Aranda P, Fernández-Ortiz M, Sayed RKA, Fernández-Gil BI, Hidalgo-Gutiérrez A, Escames G, López LC, Acuña-Castroviejo D. Díaz-Casado ME, et al. Among authors: rusanova i. Zebrafish. 2018 Feb;15(1):15-26. doi: 10.1089/zeb.2017.1479. Epub 2017 Nov 29. Zebrafish. 2018. PMID: 29185873
The Impact of Melatonin and NLRP3 Inflammasome on the Expression of microRNAs in Aged Muscle.
Sayed RK, Fernández-Ortiz M, Fernández-Martínez J, Aranda Martínez P, Guerra-Librero A, Rodríguez-Santana C, de Haro T, Escames G, Acuña-Castroviejo D, Rusanova I. Sayed RK, et al. Among authors: rusanova i. Antioxidants (Basel). 2021 Mar 27;10(4):524. doi: 10.3390/antiox10040524. Antioxidants (Basel). 2021. PMID: 33801675 Free PMC article.
30 results