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MPAPASS software enables stitched multiplex, multidimensional EV repertoire analysis and a standard framework for reporting bead-based assays.
Welsh JA, Killingsworth B, Kepley J, Traynor T, Cook S, Savage J, Marte J, Lee MJ, Maeng HM, Pleet ML, Magana S, Gorgens A, Maire CL, Lamszus K, Ricklefs FL, Merino MJ, Linehan WM, Greten T, Cooks T, Harris CC, Apolo A, Abdel-Mageed A, Ivanov AR, Trepel JB, Roth M, Tkach M, Milosavljevic A, Théry C, LeBlanc A, Berzofsky JA, Ruppin E, Aldape K, Camphausen K, Gulley JL, Ghiran I, Jacobson S, Jones JC. Welsh JA, et al. Among authors: ruppin e. Cell Rep Methods. 2022 Jan 24;2(1):100136. doi: 10.1016/j.crmeth.2021.100136. eCollection 2022 Jan 24. Cell Rep Methods. 2022. PMID: 35474866 Free PMC article.
Big data in basic and translational cancer research.
Jiang P, Sinha S, Aldape K, Hannenhalli S, Sahinalp C, Ruppin E. Jiang P, et al. Among authors: ruppin e. Nat Rev Cancer. 2022 Nov;22(11):625-639. doi: 10.1038/s41568-022-00502-0. Epub 2022 Sep 5. Nat Rev Cancer. 2022. PMID: 36064595 Free PMC article. Review.
Tumor methionine metabolism drives T-cell exhaustion in hepatocellular carcinoma.
Hung MH, Lee JS, Ma C, Diggs LP, Heinrich S, Chang CW, Ma L, Forgues M, Budhu A, Chaisaingmongkol J, Ruchirawat M, Ruppin E, Greten TF, Wang XW. Hung MH, et al. Among authors: ruppin e. Nat Commun. 2021 Mar 5;12(1):1455. doi: 10.1038/s41467-021-21804-1. Nat Commun. 2021. PMID: 33674593 Free PMC article.
Synthetic lethality-mediated precision oncology via the tumor transcriptome.
Lee JS, Nair NU, Dinstag G, Chapman L, Chung Y, Wang K, Sinha S, Cha H, Kim D, Schperberg AV, Srinivasan A, Lazar V, Rubin E, Hwang S, Berger R, Beker T, Ronai Z, Hannenhalli S, Gilbert MR, Kurzrock R, Lee SH, Aldape K, Ruppin E. Lee JS, et al. Among authors: ruppin e. Cell. 2021 Apr 29;184(9):2487-2502.e13. doi: 10.1016/j.cell.2021.03.030. Epub 2021 Apr 14. Cell. 2021. PMID: 33857424 Free PMC article.
PD-L1 recruits phospholipase C and enhances tumorigenicity of lung tumors harboring mutant forms of EGFR.
Ghosh S, Nataraj NB, Noronha A, Patkar S, Sekar A, Mukherjee S, Winograd-Katz S, Kramarski L, Verma A, Lindzen M, Garcia DD, Green J, Eisenberg G, Gil-Henn H, Basu A, Lender Y, Weiss S, Oren M, Lotem M, Geiger B, Ruppin E, Yarden Y. Ghosh S, et al. Among authors: ruppin e. Cell Rep. 2021 May 25;35(8):109181. doi: 10.1016/j.celrep.2021.109181. Cell Rep. 2021. PMID: 34038737 Free PMC article.
Nucleoporin-93 reveals a common feature of aggressive breast cancers: robust nucleocytoplasmic transport of transcription factors.
Nataraj NB, Noronha A, Lee JS, Ghosh S, Mohan Raju HR, Sekar A, Zuckerman B, Lindzen M, Tarcitano E, Srivastava S, Selitrennik M, Livneh I, Drago-Garcia D, Rueda O, Caldas C, Lev S, Geiger T, Ciechanover A, Ulitsky I, Seger R, Ruppin E, Yarden Y. Nataraj NB, et al. Among authors: ruppin e. Cell Rep. 2022 Feb 22;38(8):110418. doi: 10.1016/j.celrep.2022.110418. Cell Rep. 2022. PMID: 35196484 Free PMC article.
331 results