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Fasting induces ANGPTL4 and reduces LPL activity in human adipose tissue.
Mol Metab. 2020 Oct;40:101033. doi: 10.1016/j.molmet.2020.101033. Epub 2020 Jun 3.
Mol Metab. 2020.
PMID: 32504883
Free PMC article.
Clinical Trial.
Angiopoietin-like 4 promotes the intracellular cleavage of lipoprotein lipase by PCSK3/furin in adipocytes.
Dijk W, Ruppert PMM, Oost LJ, Kersten S.
Dijk W, et al. Among authors: ruppert pmm.
J Biol Chem. 2018 Sep 7;293(36):14134-14145. doi: 10.1074/jbc.RA118.002426. Epub 2018 Jul 18.
J Biol Chem. 2018.
PMID: 30021841
Free PMC article.
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Transcriptional profiling of PPARα-/- and CREB3L3-/- livers reveals disparate regulation of hepatoproliferative and metabolic functions of PPARα.
Ruppert PMM, Park JG, Xu X, Hur KY, Lee AH, Kersten S.
Ruppert PMM, et al.
BMC Genomics. 2019 Mar 11;20(1):199. doi: 10.1186/s12864-019-5563-y.
BMC Genomics. 2019.
PMID: 30866796
Free PMC article.
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A single day of high-fat diet feeding induces lipid accumulation and insulin resistance in brown adipose tissue in mice.
Kuipers EN, Held NM, In Het Panhuis W, Modder M, Ruppert PMM, Kersten S, Kooijman S, Guigas B, Houtkooper RH, Rensen PCN, Boon MR.
Kuipers EN, et al. Among authors: ruppert pmm.
Am J Physiol Endocrinol Metab. 2019 Nov 1;317(5):E820-E830. doi: 10.1152/ajpendo.00123.2019. Epub 2019 Aug 6.
Am J Physiol Endocrinol Metab. 2019.
PMID: 31386566
Free article.
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Characterization of ANGPTL4 function in macrophages and adipocytes using Angptl4-knockout and Angptl4-hypomorphic mice.
Oteng AB, Ruppert PMM, Boutens L, Dijk W, van Dierendonck XAMH, Olivecrona G, Stienstra R, Kersten S.
Oteng AB, et al. Among authors: ruppert pmm.
J Lipid Res. 2019 Oct;60(10):1741-1754. doi: 10.1194/jlr.M094128. Epub 2019 Aug 13.
J Lipid Res. 2019.
PMID: 31409739
Free PMC article.
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A lipase fusion feasts on fat.
Ruppert PMM, Kersten S.
Ruppert PMM, et al.
J Biol Chem. 2020 Mar 6;295(10):2913-2914. doi: 10.1074/jbc.H120.012744.
J Biol Chem. 2020.
PMID: 32144145
Free PMC article.
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Mechanisms of hepatic fatty acid oxidation and ketogenesis during fasting.
Ruppert PMM, Kersten S.
Ruppert PMM, et al.
Trends Endocrinol Metab. 2024 Feb;35(2):107-124. doi: 10.1016/j.tem.2023.10.002. Epub 2023 Nov 6.
Trends Endocrinol Metab. 2024.
PMID: 37940485
Review.
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Cold-induced expression of a truncated adenylyl cyclase 3 acts as rheostat to brown fat function.
Khani S, Topel H, Kardinal R, Tavanez AR, Josephrajan A, Larsen BDM, Gaudry MJ, Leyendecker P, Egedal NM, Güller AS, Stanic N, Ruppert PMM, Gaziano I, Hansmeier NR, Schmidt E, Klemm P, Vagliano LM, Stahl R, Duthie F, Krause JH, Bici A, Engelhard CA, Gohlke S, Frommolt P, Gnad T, Rada-Iglesias A, Pradas-Juni M, Schulz TJ, Wunderlich FT, Pfeifer A, Bartelt A, Jastroch M, Wachten D, Kornfeld JW.
Khani S, et al. Among authors: ruppert pmm.
Nat Metab. 2024 Apr 29. doi: 10.1038/s42255-024-01033-8. Online ahead of print.
Nat Metab. 2024.
PMID: 38684889
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