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Fungal Lanosterol 14α-demethylase: A target for next-generation antifungal design.
Biochim Biophys Acta Proteins Proteom. 2020 Mar;1868(3):140206. doi: 10.1016/j.bbapap.2019.02.008. Epub 2019 Mar 6.
Biochim Biophys Acta Proteins Proteom. 2020.
PMID: 30851431
Review.
Heterologous Expression of Full-Length Lanosterol 14α-Demethylases of Prominent Fungal Pathogens Candida albicans and Candida glabrata Provides Tools for Antifungal Discovery.
Keniya MV, Ruma YN, Tyndall JDA, Monk BC.
Keniya MV, et al. Among authors: ruma yn.
Antimicrob Agents Chemother. 2018 Oct 24;62(11):e01131-18. doi: 10.1128/AAC.01131-18. Print 2018 Nov.
Antimicrob Agents Chemother. 2018.
PMID: 30126959
Free PMC article.
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Structural Insights into the Azole Resistance of the Candida albicans Darlington Strain Using Saccharomyces cerevisiae Lanosterol 14α-Demethylase as a Surrogate.
Graham DO, Wilson RK, Ruma YN, Keniya MV, Tyndall JDA, Monk BC.
Graham DO, et al. Among authors: ruma yn.
J Fungi (Basel). 2021 Oct 24;7(11):897. doi: 10.3390/jof7110897.
J Fungi (Basel). 2021.
PMID: 34829185
Free PMC article.
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Characterisation of Candida parapsilosis CYP51 as a Drug Target Using Saccharomyces cerevisiae as Host.
Ruma YN, Keniya MV, Tyndall JDA, Monk BC.
Ruma YN, et al.
J Fungi (Basel). 2022 Jan 10;8(1):69. doi: 10.3390/jof8010069.
J Fungi (Basel). 2022.
PMID: 35050009
Free PMC article.
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MicroED structure of the C11 cysteine protease Clostripain.
Ruma YN, Bu G, Gonen T.
Ruma YN, et al.
bioRxiv [Preprint]. 2024 Jan 5:2024.01.04.574240. doi: 10.1101/2024.01.04.574240.
bioRxiv. 2024.
PMID: 38260293
Free PMC article.
Preprint.
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Exploring Cryptococcus neoformans CYP51 and Its Cognate Reductase as a Drug Target.
Ruma YN, Keniya MV, Monk BC.
Ruma YN, et al.
J Fungi (Basel). 2022 Nov 28;8(12):1256. doi: 10.3390/jof8121256.
J Fungi (Basel). 2022.
PMID: 36547589
Free PMC article.
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Identification of bioactive metabolites and evaluation of in vitro anti-inflammatory and in vivo antinociceptive and antiarthritic activities of endophyte fungi isolated from Elaeocarpus floribundus blume.
Mazumder K, Ruma YN, Akter R, Aktar A, Hossain MM, Shahina Z, Mazumdar S, Kerr PG.
Mazumder K, et al. Among authors: ruma yn.
J Ethnopharmacol. 2021 Jun 12;273:113975. doi: 10.1016/j.jep.2021.113975. Epub 2021 Feb 27.
J Ethnopharmacol. 2021.
PMID: 33652111
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