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Metformin exhibits antineoplastic effects on Pten-deficient endometrial cancer by interfering with TGF-β and p38/ERK MAPK signalling.
Biomed Pharmacother. 2023 Dec;168:115817. doi: 10.1016/j.biopha.2023.115817. Epub 2023 Nov 3.
Biomed Pharmacother. 2023.
PMID: 37925934
Free article.
In Vivo Intra-Uterine Delivery of TAT-Fused Cre Recombinase and CRISPR/Cas9 Editing System in Mice Unveil Histopathology of Pten/p53-Deficient Endometrial Cancers.
Navaridas R, Vidal-Sabanés M, Ruiz-Mitjana A, Altés G, Perramon-Güell A, Yeramian A, Egea J, Encinas M, Gatius S, Matias-Guiu X, Dolcet X.
Navaridas R, et al. Among authors: ruiz mitjana a.
Adv Sci (Weinh). 2023 Nov;10(32):e2303134. doi: 10.1002/advs.202303134. Epub 2023 Sep 25.
Adv Sci (Weinh). 2023.
PMID: 37749866
Free PMC article.
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Transient and DNA-free in vivo CRISPR/Cas9 genome editing for flexible modeling of endometrial carcinogenesis.
Navaridas R, Vidal-Sabanés M, Ruiz-Mitjana A, Perramon-Güell A, Megino-Luque C, Llobet-Navas D, Matias-Guiu X, Egea J, Encinas M, Bardia L, Colombelli J, Dolcet X.
Navaridas R, et al. Among authors: ruiz mitjana a.
Cancer Commun (Lond). 2023 May;43(5):620-624. doi: 10.1002/cac2.12409. Epub 2023 Feb 10.
Cancer Commun (Lond). 2023.
PMID: 36762520
Free PMC article.
No abstract available.
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Lack of extracellular matrix switches TGF-β induced apoptosis of endometrial cells to epithelial to mesenchymal transition.
Ruiz-Mitjana A, Navaridas R, Vidal-Sabanés M, Perramon-Güell A, Yeramian A, Felip I, Eritja N, Egea J, Encinas M, Matias-Guiu X, Dolcet X.
Ruiz-Mitjana A, et al.
Sci Rep. 2022 Sep 1;12(1):14821. doi: 10.1038/s41598-022-18976-1.
Sci Rep. 2022.
PMID: 36050359
Free PMC article.
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Endometrial PTEN Deficiency Leads to SMAD2/3 Nuclear Translocation.
Eritja N, Navaridas R, Ruiz-Mitjana A, Vidal-Sabanés M, Egea J, Encinas M, Matias-Guiu X, Dolcet X.
Eritja N, et al. Among authors: ruiz mitjana a.
Cancers (Basel). 2021 Oct 5;13(19):4990. doi: 10.3390/cancers13194990.
Cancers (Basel). 2021.
PMID: 34638474
Free PMC article.
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