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Page 1
Recent patents on alphavirus protein expression and vector production.
Aranda A, Ruiz-Guillen M, Quetglas JI, Bezunartea J, Casales E, Smerdou C. Aranda A, et al. Among authors: ruiz guillen m. Recent Pat Biotechnol. 2011 Dec;5(3):212-26. doi: 10.2174/187220811797579060. Recent Pat Biotechnol. 2011. PMID: 22360469 Review.
Alphavirus vectors for cancer therapy.
Quetglas JI, Ruiz-Guillen M, Aranda A, Casales E, Bezunartea J, Smerdou C. Quetglas JI, et al. Among authors: ruiz guillen m. Virus Res. 2010 Nov;153(2):179-96. doi: 10.1016/j.virusres.2010.07.027. Epub 2010 Aug 6. Virus Res. 2010. PMID: 20692305 Review.
Strict requirement for vector-induced type I interferon in efficacious antitumor responses to virally encoded IL12.
Melero I, Quetglas JI, Reboredo M, Dubrot J, Rodriguez-Madoz JR, Mancheño U, Casales E, Riezu-Boj JI, Ruiz-Guillen M, Ochoa MC, Sanmamed MF, Thieblemont N, Smerdou C, Hervas-Stubbs S. Melero I, et al. Among authors: ruiz guillen m. Cancer Res. 2015 Feb 1;75(3):497-507. doi: 10.1158/0008-5472.CAN-13-3356. Epub 2014 Dec 19. Cancer Res. 2015. PMID: 25527611
Capsid-deficient alphaviruses generate propagative infectious microvesicles at the plasma membrane.
Ruiz-Guillen M, Gabev E, Quetglas JI, Casales E, Ballesteros-Briones MC, Poutou J, Aranda A, Martisova E, Bezunartea J, Ondiviela M, Prieto J, Hernandez-Alcoceba R, Abrescia NG, Smerdou C. Ruiz-Guillen M, et al. Cell Mol Life Sci. 2016 Oct;73(20):3897-916. doi: 10.1007/s00018-016-2230-1. Epub 2016 Apr 27. Cell Mol Life Sci. 2016. PMID: 27117550 Free PMC article.
Semliki forest virus expressing interleukin-12 induces antiviral and antitumoral responses in woodchucks with chronic viral hepatitis and hepatocellular carcinoma.
Rodriguez-Madoz JR, Liu KH, Quetglas JI, Ruiz-Guillen M, Otano I, Crettaz J, Butler SD, Bellezza CA, Dykes NL, Tennant BC, Prieto J, González-Aseguinolaza G, Smerdou C, Menne S. Rodriguez-Madoz JR, et al. Among authors: ruiz guillen m. J Virol. 2009 Dec;83(23):12266-78. doi: 10.1128/JVI.01597-09. Epub 2009 Sep 9. J Virol. 2009. PMID: 19740992 Free PMC article.
Neurotropic alphaviruses can propagate without capsid.
Ruiz-Guillen M, Abrescia NG, Smerdou C. Ruiz-Guillen M, et al. Oncotarget. 2017 Feb 7;8(6):8999-9000. doi: 10.18632/oncotarget.13993. Oncotarget. 2017. PMID: 28129638 Free PMC article. No abstract available.