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Functional roles of Akt signaling in mouse skin tumorigenesis.
Segrelles C, Ruiz S, Perez P, Murga C, Santos M, Budunova IV, Martínez J, Larcher F, Slaga TJ, Gutkind JS, Jorcano JL, Paramio JM. Segrelles C, et al. Among authors: ruiz s. Oncogene. 2002 Jan 3;21(1):53-64. doi: 10.1038/sj.onc.1205032. Oncogene. 2002. PMID: 11791176
Unexpected roles for pRb in mouse skin carcinogenesis.
Ruiz S, Santos M, Lara MF, Segrelles C, Ballestín C, Paramio JM. Ruiz S, et al. Cancer Res. 2005 Nov 1;65(21):9678-86. doi: 10.1158/0008-5472.CAN-05-1853. Cancer Res. 2005. PMID: 16266987
p107 acts as a tumor suppressor in pRb-deficient epidermis.
Lara MF, Santos M, Ruiz S, Segrelles C, Moral M, Martínez-Cruz AB, Hernández P, Martínez-Palacio J, Lorz C, García-Escudero R, Paramio JM. Lara MF, et al. Among authors: ruiz s. Mol Carcinog. 2008 Feb;47(2):105-13. doi: 10.1002/mc.20367. Mol Carcinog. 2008. PMID: 17932945
Deregulated activity of Akt in epithelial basal cells induces spontaneous tumors and heightened sensitivity to skin carcinogenesis.
Segrelles C, Lu J, Hammann B, Santos M, Moral M, Cascallana JL, Lara MF, Rho O, Carbajal S, Traag J, Beltrán L, Martínez-Cruz AB, García-Escudero R, Lorz C, Ruiz S, Bravo A, Paramio JM, DiGiovanni J. Segrelles C, et al. Among authors: ruiz s. Cancer Res. 2007 Nov 15;67(22):10879-88. doi: 10.1158/0008-5472.CAN-07-2564. Cancer Res. 2007. PMID: 18006833
920 results