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Page 1
Antibody targeting of E3 ubiquitin ligases for receptor degradation.
Marei H, Tsai WK, Kee YS, Ruiz K, He J, Cox C, Sun T, Penikalapati S, Dwivedi P, Choi M, Kan D, Saenz-Lopez P, Dorighi K, Zhang P, Kschonsak YT, Kljavin N, Amin D, Kim I, Mancini AG, Nguyen T, Wang C, Janezic E, Doan A, Mai E, Xi H, Gu C, Heinlein M, Biehs B, Wu J, Lehoux I, Harris S, Comps-Agrar L, Seshasayee D, de Sauvage FJ, Grimmer M, Li J, Agard NJ, de Sousa E Melo F. Marei H, et al. Among authors: ruiz k. Nature. 2022 Oct;610(7930):182-189. doi: 10.1038/s41586-022-05235-6. Epub 2022 Sep 21. Nature. 2022. PMID: 36131013 Free PMC article.
Potent and selective binders of the E3 ubiquitin ligase ZNRF3 stimulate Wnt signaling and intestinal organoid growth.
Kschonsak YT, Gao X, Miller SE, Hwang S, Marei H, Wu P, Li Y, Ruiz K, Dorighi K, Holokai L, Perampalam P, Tsai WK, Kee YS, Agard NJ, Harris SF, Hannoush RN, de Sousa E Melo F. Kschonsak YT, et al. Among authors: ruiz k. Cell Chem Biol. 2023 Dec 5:S2451-9456(23)00421-X. doi: 10.1016/j.chembiol.2023.11.006. Online ahead of print. Cell Chem Biol. 2023. PMID: 38056465
Amygdala inhibitory neurons as loci for translation in emotional memories.
Shrestha P, Shan Z, Mamcarz M, Ruiz KSA, Zerihoun AT, Juan CY, Herrero-Vidal PM, Pelletier J, Heintz N, Klann E. Shrestha P, et al. Nature. 2020 Oct;586(7829):407-411. doi: 10.1038/s41586-020-2793-8. Epub 2020 Oct 7. Nature. 2020. PMID: 33029009 Free PMC article.
Implementing precision oncology in Latin America to improve patient outcomes: the status quo and a call to action for key stakeholders and decision-makers.
de Castilla EMR, Mayrides M, González H, Vidangossy F, Corbeaux T, Ortiz N, Amaya C, Nuñez A, Jimbo DFJ, Ayensa A, Galindo M, Ruiz K, Pérez JM. de Castilla EMR, et al. Among authors: ruiz k. Ecancermedicalscience. 2024 Jan 8;18:1653. doi: 10.3332/ecancer.2024.1653. eCollection 2024. Ecancermedicalscience. 2024. PMID: 38425763 Free PMC article.
Applying data science methodologies with artificial intelligence variant reinterpretation to map and estimate genetic disorder prevalence utilizing clinical data.
Jackson S, Freeman R, Noronha A, Jamil H, Chavez E, Carmichael J, Ruiz KM, Miller C, Benke S, Perrot R, Hockley M, Murphy K, Casillan A, Radanovich L, Deforest R, Nunes ME, Galarreta-Aima C, Sidlow R, Einhorn Y, Woods J. Jackson S, et al. Among authors: ruiz km. Am J Med Genet A. 2024 May;194(5):e63505. doi: 10.1002/ajmg.a.63505. Epub 2024 Jan 2. Am J Med Genet A. 2024. PMID: 38168469
121 results