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Type 2 diabetes candidate genes, including PAX5, cause impaired insulin secretion in human pancreatic islets.
Bacos K, Perfilyev A, Karagiannopoulos A, Cowan E, Ofori JK, Bertonnier-Brouty L, Rönn T, Lindqvist A, Luan C, Ruhrmann S, Ngara M, Nilsson Å, Gheibi S, Lyons CL, Lagerstedt JO, Barghouth M, Esguerra JL, Volkov P, Fex M, Mulder H, Wierup N, Krus U, Artner I, Eliasson L, Prasad RB, Cataldo LR, Ling C. Bacos K, et al. Among authors: ruhrmann s. J Clin Invest. 2023 Feb 15;133(4):e163612. doi: 10.1172/JCI163612. J Clin Invest. 2023. PMID: 36656641 Free PMC article.
Genes with epigenetic alterations in human pancreatic islets impact mitochondrial function, insulin secretion, and type 2 diabetes.
Rönn T, Ofori JK, Perfilyev A, Hamilton A, Pircs K, Eichelmann F, Garcia-Calzon S, Karagiannopoulos A, Stenlund H, Wendt A, Volkov P, Schulze MB, Mulder H, Eliasson L, Ruhrmann S, Bacos K, Ling C. Rönn T, et al. Among authors: ruhrmann s. Nat Commun. 2023 Dec 12;14(1):8040. doi: 10.1038/s41467-023-43719-9. Nat Commun. 2023. PMID: 38086799 Free PMC article.
Genome-wide association study identifies 30 obsessive-compulsive disorder associated loci.
Strom NI, Gerring ZF, Galimberti M, Yu D, Halvorsen MW, Abdellaoui A, Rodriguez-Fontenla C, Sealock JM, Bigdeli T, Coleman JR, Mahjani B, Thorp JG, Bey K, Burton CL, Luykx JJ, Zai G, Alemany S, Andre C, Askland KD, Banaj N, Barlassina C, Nissen JB, Bienvenu OJ, Black D, Bloch MH, Boberg J, Børte S, Bosch R, Breen M, Brennan BP, Brentani H, Buxbaum JD, Bybjerg-Grauholm J, Byrne EM, Cabana-Dominguez J, Camarena B, Camarena A, Cappi C, Carracedo A, Casas M, Cavallini MC, Ciullo V, Cook EH, Crosby J, Cullen BA, De Schipper EJ, Delorme R, Djurovic S, Elias JA, Estivill X, Falkenstein MJ, Fundin BT, Garner L, German C, Gironda C, Goes FS, Grados MA, Grove J, Guo W, Haavik J, Hagen K, Harrington K, Havdahl A, Höffler KD, Hounie AG, Hucks D, Hultman C, Janecka M, Jenike E, Karlsson EK, Kelley K, Klawohn J, Krasnow JE, Krebs K, Lange C, Lanzagorta N, Levey D, Lindblad-Toh K, Macciardi F, Maher B, Mathes B, McArthur E, McGregor N, McLaughlin NC, Meier S, Miguel EC, Mulhern M, Nestadt PS, Nurmi EL, O'Connell KS, Osiecki L, Ousdal OT, Palviainen T, Pedersen NL, Piras F, Piras F, Potluri S, Rabionet R, Ramirez A, Rauch S, Reichenberg A, Riddle MA, Ripke S, Rosário MC, Sampaio AS, Schiele MA, S… See abstract for full author list ➔ Strom NI, et al. Among authors: ruhrmann s. medRxiv [Preprint]. 2024 Mar 13:2024.03.13.24304161. doi: 10.1101/2024.03.13.24304161. medRxiv. 2024. PMID: 38712091 Free PMC article. Preprint.
Distinct multimodal biological and functional profiles of symptom-based subgroups in recent-onset psychosis.
Koutsouleris N, Buciuman MO, Vetter CS, Weyer CFC, Zhutovsky P, Perdomo ST, Khuntia A, Milaneschi Y, Popovic D, Ruef A, Dwyer D, Chisholm K, Kambeitz L, Antonucci L, Ruhrmann S, Kambeitz J, Riecher-Rössler A, Upthegrove R, Salokangas R, Hietala J, Pantelis C, Lencer R, Meisenzahl E, Wood S, Brambilla P, Borgwardt S, Bertolino A, Falkai P. Koutsouleris N, et al. Among authors: ruhrmann s. Res Sq [Preprint]. 2024 Mar 13:rs.3.rs-3949072. doi: 10.21203/rs.3.rs-3949072/v1. Res Sq. 2024. PMID: 38559014 Free PMC article. Preprint.
Neurocognitive skills and vulnerability for psychosis in depression and across the psychotic spectrum: findings from the PRONIA Consortium - CORRIGENDUM.
Bonivento C, Kambeitz-Ilankovic L, Maggioni E, Borgwardt S, Lencer R, Meisenzahl E, Kambeitz J, Ruhrmann S, Salokangas RKR, Bertolino A, Stainton A, Wenzel J, Pantelis C, Wood SJ, Upthegrove R, Koutsouleris N, Brambilla P; PRONIA Consortium. Bonivento C, et al. Among authors: ruhrmann s. Br J Psychiatry. 2024 May;224(5):185. doi: 10.1192/bjp.2024.43. Br J Psychiatry. 2024. PMID: 38497099 No abstract available.
Alterations of Functional Connectivity Dynamics in Affective and Psychotic Disorders.
Hoheisel L, Kambeitz-Ilankovic L, Wenzel J, Haas SS, Antonucci LA, Ruef A, Penzel N, Schultze-Lutter F, Lichtenstein T, Rosen M, Dwyer DB, Salokangas RKR, Lencer R, Brambilla P, Borgwardt S, Wood SJ, Upthegrove R, Bertolino A, Ruhrmann S, Meisenzahl E, Koutsouleris N, Fink GR, Daun S, Kambeitz J; PRONIA Consortium. Hoheisel L, et al. Among authors: ruhrmann s. Biol Psychiatry Cogn Neurosci Neuroimaging. 2024 Mar 8:S2451-9022(24)00065-X. doi: 10.1016/j.bpsc.2024.02.013. Online ahead of print. Biol Psychiatry Cogn Neurosci Neuroimaging. 2024. PMID: 38461964 Free article.
Associations between disturbed sleep and attenuated psychotic experiences in people at clinical high risk for psychosis.
Formica MJC, Fuller-Tyszkiewicz M, Reininghaus U, Kempton M, Delespaul P, de Haan L, Nelson B, Mikocka-Walus A, Olive L, Ruhrmann S, Rutten B, Riecher-Rössler A, Sachs G, Valmaggia L, van der Gaag M, McGuire P, van Os J; EU-GEI High-Risk Study; Hartmann JA. Formica MJC, et al. Among authors: ruhrmann s. Psychol Med. 2024 Mar 7:1-10. doi: 10.1017/S0033291724000400. Online ahead of print. Psychol Med. 2024. PMID: 38450445
Clinical high risk state of major depressive episodes: Assessment of prodromal phase, its occurrence, duration and symptom patterns by the instrument the DEpression Early Prediction-INventory (DEEP-IN).
Meisenzahl E, Wege N, Stegmüller V, Schulte-Körne G, Greimel E, Dannlowski U, Hahn T, Romer G, Romanos M, Deserno L, Klingele C, Theisen C, Kieckhäfer C, Forstner A, Ruhrmann S, Schultze-Lutter F. Meisenzahl E, et al. Among authors: ruhrmann s. J Affect Disord. 2024 Apr 15;351:403-413. doi: 10.1016/j.jad.2023.12.084. Epub 2024 Jan 4. J Affect Disord. 2024. PMID: 38181843 Free article.
Algorithmic fairness in precision psychiatry: analysis of prediction models in individuals at clinical high risk for psychosis.
Şahin D, Kambeitz-Ilankovic L, Wood S, Dwyer D, Upthegrove R, Salokangas R, Borgwardt S, Brambilla P, Meisenzahl E, Ruhrmann S, Schultze-Lutter F, Lencer R, Bertolino A, Pantelis C, Koutsouleris N, Kambeitz J; PRONIA Study Group. Şahin D, et al. Among authors: ruhrmann s. Br J Psychiatry. 2024 Feb;224(2):55-65. doi: 10.1192/bjp.2023.141. Br J Psychiatry. 2024. PMID: 37936347
Neurocognitive skills and vulnerability for psychosis in depression and across the psychotic spectrum: findings from the PRONIA Consortium.
Bonivento C, Kambeitz-Ilankovic L, Maggioni E, Borgwardt S, Lencer R, Meisenzahl E, Kambeitz J, Ruhrmann S, Salokangas RKR, Bertolino A, Stainton A, Wenzel J, Pantelis C, Wood SJ, Upthegrove R, Koutsouleris N, Brambilla P; PRONIA Consortium. Bonivento C, et al. Among authors: ruhrmann s. Br J Psychiatry. 2023 Oct;223(4):485-492. doi: 10.1192/bjp.2023.98. Epub 2023 Oct 17. Br J Psychiatry. 2023. PMID: 37846967
243 results