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B cell signatures and tertiary lymphoid structures contribute to outcome in head and neck squamous cell carcinoma.
Nat Commun. 2021 Jun 7;12(1):3349. doi: 10.1038/s41467-021-23355-x.
Nat Commun. 2021.
PMID: 34099645
Free PMC article.
Characteristics of Malignant Pleural Effusion Resident CD8+ T Cells from a Heterogeneous Collection of Tumors.
Dhupar R, Okusanya OT, Eisenberg SH, Monaco SE, Ruffin AT, Liu D, Luketich JD, Kammula US, Bruno TC, Lotze MT, Soloff AC.
Dhupar R, et al. Among authors: ruffin at.
Int J Mol Sci. 2020 Aug 27;21(17):6178. doi: 10.3390/ijms21176178.
Int J Mol Sci. 2020.
PMID: 32867034
Free PMC article.
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Bifurcated monocyte states are predictive of mortality in severe COVID-19.
Cillo AR, Somasundaram A, Shan F, Cardello C, Workman CJ, Kitsios GD, Ruffin A, Kunning S, Lampenfeld C, Onkar S, Grebinoski S, Deshmukh G, Methe B, Liu C, Nambulli S, Andrews L, Duprex WP, Joglekar AV, Benos PV, Ray P, Ray A, McVerry BJ, Zhang Y, Lee JS, Das J, Singh H, Morris A, Bruno TC, Vignali DAA.
Cillo AR, et al.
bioRxiv [Preprint]. 2021 Feb 10:2021.02.10.430499. doi: 10.1101/2021.02.10.430499.
bioRxiv. 2021.
PMID: 33594364
Free PMC article.
Preprint.
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People critically ill with COVID-19 exhibit peripheral immune profiles predictive of mortality and reflective of SARS-CoV-2 lung viral burden.
Cillo AR, Somasundaram A, Shan F, Cardello C, Workman CJ, Kitsios GD, Ruffin AT, Kunning S, Lampenfeld C, Onkar S, Grebinoski S, Deshmukh G, Methe B, Liu C, Nambulli S, Andrews LP, Duprex WP, Joglekar AV, Benos PV, Ray P, Ray A, McVerry BJ, Zhang Y, Lee JS, Das J, Singh H, Morris A, Bruno TC, Vignali DAA.
Cillo AR, et al. Among authors: ruffin at.
Cell Rep Med. 2021 Dec 21;2(12):100476. doi: 10.1016/j.xcrm.2021.100476. Epub 2021 Dec 2.
Cell Rep Med. 2021.
PMID: 34873589
Free PMC article.
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Phase I Trial of Cetuximab, Radiotherapy, and Ipilimumab in Locally Advanced Head and Neck Cancer.
Ferris RL, Moskovitz J, Kunning S, Ruffin AT, Reeder C, Ohr J, Gooding WE, Kim S, Karlovits BJ, Vignali DAA, Duvvuri U, Johnson JT, Petro D, Heron DE, Clump DA, Bruno TC, Bauman JE.
Ferris RL, et al. Among authors: ruffin at.
Clin Cancer Res. 2022 Apr 1;28(7):1335-1344. doi: 10.1158/1078-0432.CCR-21-0426.
Clin Cancer Res. 2022.
PMID: 35091445
Free PMC article.
Clinical Trial.
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Improving head and neck cancer therapies by immunomodulation of the tumour microenvironment.
Ruffin AT, Li H, Vujanovic L, Zandberg DP, Ferris RL, Bruno TC.
Ruffin AT, et al.
Nat Rev Cancer. 2023 Mar;23(3):173-188. doi: 10.1038/s41568-022-00531-9. Epub 2022 Dec 1.
Nat Rev Cancer. 2023.
PMID: 36456755
Free PMC article.
Review.
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IL15 and IL21: Better When Membrane-Tethered Together on Antitumor T Cells.
Ruffin AT, Wittling MC, Cole AC, Paulos CM.
Ruffin AT, et al.
Clin Cancer Res. 2024 Apr 15;30(8):1431-1433. doi: 10.1158/1078-0432.CCR-23-3466.
Clin Cancer Res. 2024.
PMID: 38289325
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