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NPM1c alters FLT3-D835Y localization and signaling in acute myeloid leukemia.
Rudorf A, Müller TA, Klingeberg C, Kreutmair S, Poggio T, Gorantla SP, Rückert T, Schmitt-Graeff A, Gengenbacher A, Paschka P, Baldus C, Zeiser R, Vassiliou GS, Bradley A, Duyster J, Illert AL. Rudorf A, et al. Blood. 2019 Jul 25;134(4):383-388. doi: 10.1182/blood.2018883140. Epub 2019 Jun 11. Blood. 2019. PMID: 31186273 Free PMC article.
PIM1 inhibition effectively enhances plerixafor-induced HSC mobilization by counteracting CXCR4 upregulation and blocking CXCL12 secretion.
Müller TA, Pennisi S, Zwick A, Decker S, Klein C, Rister B, Rudorf A, Kissel S, Follo M, Wäsch R, Illert AL, Pfeifer D, Oostendorp R, Waskow C, Dierks C, Duyster J. Müller TA, et al. Among authors: rudorf a. Leukemia. 2019 May;33(5):1296-1301. doi: 10.1038/s41375-019-0428-6. Epub 2019 Feb 28. Leukemia. 2019. PMID: 30816332 No abstract available.
Modularized CRISPR/dCas9 effector toolkit for target-specific gene regulation.
Agne M, Blank I, Emhardt AJ, Gäbelein CG, Gawlas F, Gillich N, Gonschorek P, Juretschke TJ, Krämer SD, Louis N, Müller A, Rudorf A, Schäfer LM, Scheidmann MC, Schmunk LJ, Schwenk PM, Stammnitz MR, Warmer PM, Weber W, Fischer A, Kaufmann B, Wagner HJ, Radziwill G. Agne M, et al. Among authors: rudorf a. ACS Synth Biol. 2014 Dec 19;3(12):986-9. doi: 10.1021/sb500035y. ACS Synth Biol. 2014. PMID: 25524106