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Gut microbiome-mediated bile acid metabolism regulates liver cancer via NKT cells.
Ma C, Han M, Heinrich B, Fu Q, Zhang Q, Sandhu M, Agdashian D, Terabe M, Berzofsky JA, Fako V, Ritz T, Longerich T, Theriot CM, McCulloch JA, Roy S, Yuan W, Thovarai V, Sen SK, Ruchirawat M, Korangy F, Wang XW, Trinchieri G, Greten TF. Ma C, et al. Among authors: ruchirawat m. Science. 2018 May 25;360(6391):eaan5931. doi: 10.1126/science.aan5931. Science. 2018. PMID: 29798856 Free PMC article.
Gut Microbiome Directs Hepatocytes to Recruit MDSCs and Promote Cholangiocarcinoma.
Zhang Q, Ma C, Duan Y, Heinrich B, Rosato U, Diggs LP, Ma L, Roy S, Fu Q, Brown ZJ, Wabitsch S, Thovarai V, Fu J, Feng D, Ruf B, Cui LL, Subramanyam V, Frank KM, Wang S, Kleiner DE, Ritz T, Rupp C, Gao B, Longerich T, Kroemer A, Wang XW, Ruchirawat M, Korangy F, Schnabl B, Trinchieri G, Greten TF. Zhang Q, et al. Among authors: ruchirawat m. Cancer Discov. 2021 May;11(5):1248-1267. doi: 10.1158/2159-8290.CD-20-0304. Epub 2020 Dec 15. Cancer Discov. 2021. PMID: 33323397 Free PMC article.
Tumor methionine metabolism drives T-cell exhaustion in hepatocellular carcinoma.
Hung MH, Lee JS, Ma C, Diggs LP, Heinrich S, Chang CW, Ma L, Forgues M, Budhu A, Chaisaingmongkol J, Ruchirawat M, Ruppin E, Greten TF, Wang XW. Hung MH, et al. Among authors: ruchirawat m. Nat Commun. 2021 Mar 5;12(1):1455. doi: 10.1038/s41467-021-21804-1. Nat Commun. 2021. PMID: 33674593 Free PMC article.
Integration of adeno-associated virus (AAV) into the genomes of most Thai and Mongolian liver cancer patients does not induce oncogenesis.
Schäffer AA, Dominguez DA, Chapman LM, Gertz EM, Budhu A, Forgues M, Chaisaingmongkol J, Rabibhadana S, Pupacdi B, Wu X, Bayarsaikhan E, Harris CC, Ruchirawat M, Ruppin E, Wang XW. Schäffer AA, et al. Among authors: ruchirawat m. BMC Genomics. 2021 Nov 11;22(1):814. doi: 10.1186/s12864-021-08098-9. BMC Genomics. 2021. PMID: 34763675 Free PMC article.
Multiregional single-cell dissection of tumor and immune cells reveals stable lock-and-key features in liver cancer.
Ma L, Heinrich S, Wang L, Keggenhoff FL, Khatib S, Forgues M, Kelly M, Hewitt SM, Saif A, Hernandez JM, Mabry D, Kloeckner R, Greten TF, Chaisaingmongkol J, Ruchirawat M, Marquardt JU, Wang XW. Ma L, et al. Among authors: ruchirawat m. Nat Commun. 2022 Dec 7;13(1):7533. doi: 10.1038/s41467-022-35291-5. Nat Commun. 2022. PMID: 36476645 Free PMC article.
LTβR signalling preferentially accelerates oncogenic AKT-initiated liver tumours.
Scarzello AJ, Jiang Q, Back T, Dang H, Hodge D, Hanson C, Subleski J, Weiss JM, Stauffer JK, Chaisaingmongkol J, Rabibhadana S, Ruchirawat M, Ortaldo J, Wang XW, Norris PS, Ware CF, Wiltrout RH. Scarzello AJ, et al. Among authors: ruchirawat m. Gut. 2016 Oct;65(10):1765-75. doi: 10.1136/gutjnl-2014-308810. Epub 2015 Jul 23. Gut. 2016. PMID: 26206664 Free PMC article.
Urinary Metabolites Diagnostic and Prognostic of Intrahepatic Cholangiocarcinoma.
Haznadar M, Diehl CM, Parker AL, Krausz KW, Bowman ED, Rabibhadana S, Forgues M, Bhudhisawasdi V, Gonzalez FJ, Mahidol C, Budhu A, Wang XW, Ruchirawat M, Harris CC. Haznadar M, et al. Among authors: ruchirawat m. Cancer Epidemiol Biomarkers Prev. 2019 Oct;28(10):1704-1711. doi: 10.1158/1055-9965.EPI-19-0453. Epub 2019 Jul 29. Cancer Epidemiol Biomarkers Prev. 2019. PMID: 31358519 Free PMC article.
125 results