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IL-2 and Beyond in Cancer Immunotherapy.
Wrangle JM, Patterson A, Johnson CB, Neitzke DJ, Mehrotra S, Denlinger CE, Paulos CM, Li Z, Cole DJ, Rubinstein MP. Wrangle JM, et al. Among authors: rubinstein mp. J Interferon Cytokine Res. 2018 Feb;38(2):45-68. doi: 10.1089/jir.2017.0101. J Interferon Cytokine Res. 2018. PMID: 29443657 Free PMC article. Review.
Soluble IL-15/IL-15Rα complexes in human serum.
Cole DJ, Rubinstein MP. Cole DJ, et al. Among authors: rubinstein mp. Blood. 2012 Jul 5;120(1):1-2. doi: 10.1182/blood-2012-04-425306. Blood. 2012. PMID: 22767572 Free article.
Interleukin-12 enhances the function and anti-tumor activity in murine and human CD8(+) T cells.
Rubinstein MP, Su EW, Suriano S, Cloud CA, Andrijauskaite K, Kesarwani P, Schwartz KM, Williams KM, Johnson CB, Li M, Scurti GM, Salem ML, Paulos CM, Garrett-Mayer E, Mehrotra S, Cole DJ. Rubinstein MP, et al. Cancer Immunol Immunother. 2015 May;64(5):539-49. doi: 10.1007/s00262-015-1655-y. Epub 2015 Feb 13. Cancer Immunol Immunother. 2015. PMID: 25676709 Free PMC article.
IL-2Rα mediates temporal regulation of IL-2 signaling and enhances immunotherapy.
Su EW, Moore CJ, Suriano S, Johnson CB, Songalia N, Patterson A, Neitzke DJ, Andrijauskaite K, Garrett-Mayer E, Mehrotra S, Paulos CM, Doedens AL, Goldrath AW, Li Z, Cole DJ, Rubinstein MP. Su EW, et al. Among authors: rubinstein mp. Sci Transl Med. 2015 Oct 28;7(311):311ra170. doi: 10.1126/scitranslmed.aac8155. Sci Transl Med. 2015. PMID: 26511507 Free PMC article.
Murine Th17 cells utilize IL-2 receptor gamma chain cytokines but are resistant to cytokine withdrawal-induced apoptosis.
Neitzke DJ, Bowers JS, Andrijauskaite K, O'Connell NS, Garrett-Mayer E, Wrangle J, Li Z, Paulos CM, Cole DJ, Rubinstein MP. Neitzke DJ, et al. Among authors: rubinstein mp. Cancer Immunol Immunother. 2017 Jun;66(6):737-751. doi: 10.1007/s00262-017-1965-3. Epub 2017 Mar 9. Cancer Immunol Immunother. 2017. PMID: 28280853 Free PMC article.
Enhanced Lymphodepletion Is Insufficient to Replace Exogenous IL2 or IL15 Therapy in Augmenting the Efficacy of Adoptively Transferred Effector CD8+ T Cells.
Johnson CB, May BR, Riesenberg BP, Suriano S, Mehrotra S, Garrett-Mayer E, Salem ML, Jeng EK, Wong HC, Paulos CM, Wrangle JM, Cole DJ, Rubinstein MP. Johnson CB, et al. Among authors: rubinstein mp. Cancer Res. 2018 Jun 1;78(11):3067-3074. doi: 10.1158/0008-5472.CAN-17-2153. Epub 2018 Apr 10. Cancer Res. 2018. PMID: 29636345 Free PMC article.
Fueling Cancer Immunotherapy With Common Gamma Chain Cytokines.
Dwyer CJ, Knochelmann HM, Smith AS, Wyatt MM, Rangel Rivera GO, Arhontoulis DC, Bartee E, Li Z, Rubinstein MP, Paulos CM. Dwyer CJ, et al. Among authors: rubinstein mp. Front Immunol. 2019 Feb 20;10:263. doi: 10.3389/fimmu.2019.00263. eCollection 2019. Front Immunol. 2019. PMID: 30842774 Free PMC article. Review.
IL-12 conditioning improves retrovirally mediated transduction efficiency of CD8+ T cells.
Andrijauskaite K, Suriano S, Cloud CA, Li M, Kesarwani P, Stefanik LS, Moxley KM, Salem ML, Garrett-Mayer E, Paulos CM, Mehrotra S, Kochenderfer JN, Cole DJ, Rubinstein MP. Andrijauskaite K, et al. Among authors: rubinstein mp. Cancer Gene Ther. 2015 Jul;22(7):360-7. doi: 10.1038/cgt.2015.28. Epub 2015 Jul 17. Cancer Gene Ther. 2015. PMID: 26182912 Free PMC article.
99 results