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Ras-mutant cancers are sensitive to small molecule inhibition of V-type ATPases in mice.
Tolani B, Celli A, Yao Y, Tan YZ, Fetter R, Liem CR, de Smith AJ, Vasanthakumar T, Bisignano P, Cotton AD, Seiple IB, Rubinstein JL, Jost M, Weissman JS. Tolani B, et al. Among authors: rubinstein jl. Nat Biotechnol. 2022 Dec;40(12):1834-1844. doi: 10.1038/s41587-022-01386-z. Epub 2022 Jul 25. Nat Biotechnol. 2022. PMID: 35879364 Free PMC article.
Structure and Roles of V-type ATPases.
Vasanthakumar T, Rubinstein JL. Vasanthakumar T, et al. Among authors: rubinstein jl. Trends Biochem Sci. 2020 Apr;45(4):295-307. doi: 10.1016/j.tibs.2019.12.007. Epub 2020 Jan 28. Trends Biochem Sci. 2020. PMID: 32001091 Review.
Multivalency transforms SARS-CoV-2 antibodies into ultrapotent neutralizers.
Rujas E, Kucharska I, Tan YZ, Benlekbir S, Cui H, Zhao T, Wasney GA, Budylowski P, Guvenc F, Newton JC, Sicard T, Semesi A, Muthuraman K, Nouanesengsy A, Aschner CB, Prieto K, Bueler SA, Youssef S, Liao-Chan S, Glanville J, Christie-Holmes N, Mubareka S, Gray-Owen SD, Rubinstein JL, Treanor B, Julien JP. Rujas E, et al. Among authors: rubinstein jl. Nat Commun. 2021 Jun 16;12(1):3661. doi: 10.1038/s41467-021-23825-2. Nat Commun. 2021. PMID: 34135340 Free PMC article.
CryoEM of endogenous mammalian V-ATPase interacting with the TLDc protein mEAK-7.
Tan YZ, Abbas YM, Wu JZ, Wu D, Keon KA, Hesketh GG, Bueler SA, Gingras AC, Robinson CV, Grinstein S, Rubinstein JL. Tan YZ, et al. Among authors: rubinstein jl. Life Sci Alliance. 2022 Jul 6;5(11):e202201527. doi: 10.26508/lsa.202201527. Print 2022 Nov. Life Sci Alliance. 2022. PMID: 35794005 Free PMC article.
Structure of V-ATPase from citrus fruit.
Tan YZ, Keon KA, Abdelaziz R, Imming P, Schulze W, Schumacher K, Rubinstein JL. Tan YZ, et al. Among authors: rubinstein jl. Structure. 2022 Oct 6;30(10):1403-1410.e4. doi: 10.1016/j.str.2022.07.006. Epub 2022 Aug 29. Structure. 2022. PMID: 36041457 Free article.
CryoEM of V-ATPases: Assembly, disassembly, and inhibition.
Wang H, Rubinstein JL. Wang H, et al. Among authors: rubinstein jl. Curr Opin Struct Biol. 2023 Jun;80:102592. doi: 10.1016/j.sbi.2023.102592. Epub 2023 Apr 17. Curr Opin Struct Biol. 2023. PMID: 37272327 Review.
Atomic model for the membrane-embedded VO motor of a eukaryotic V-ATPase.
Mazhab-Jafari MT, Rohou A, Schmidt C, Bueler SA, Benlekbir S, Robinson CV, Rubinstein JL. Mazhab-Jafari MT, et al. Among authors: rubinstein jl. Nature. 2016 Nov 3;539(7627):118-122. doi: 10.1038/nature19828. Epub 2016 Oct 24. Nature. 2016. PMID: 27776355 Free PMC article.
130 results