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In vivo anti-MUC1+ tumor activity and sequences of high-affinity anti-MUC1-SEA antibodies.
Pichinuk E, Chalik M, Benhar I, Ginat-Koton R, Ziv R, Smorodinsky NI, Haran G, Garbar C, Bensussan A, Meeker A, Guillaume T, Rubinstein DB, Wreschner DH. Pichinuk E, et al. Among authors: rubinstein db. Cancer Immunol Immunother. 2020 Jul;69(7):1337-1352. doi: 10.1007/s00262-020-02547-2. Epub 2020 Mar 26. Cancer Immunol Immunother. 2020. PMID: 32219500 Free PMC article.
Antibody targeting of cell-bound MUC1 SEA domain kills tumor cells.
Pichinuk E, Benhar I, Jacobi O, Chalik M, Weiss L, Ziv R, Sympson C, Karwa A, Smorodinsky NI, Rubinstein DB, Wreschner DH. Pichinuk E, et al. Among authors: rubinstein db. Cancer Res. 2012 Jul 1;72(13):3324-36. doi: 10.1158/0008-5472.CAN-12-0067. Epub 2012 Apr 16. Cancer Res. 2012. PMID: 22507854
MUC1-ARF-A Novel MUC1 Protein That Resides in the Nucleus and Is Expressed by Alternate Reading Frame Translation of MUC1 mRNA.
Chalick M, Jacobi O, Pichinuk E, Garbar C, Bensussan A, Meeker A, Ziv R, Zehavi T, Smorodinsky NI, Hilkens J, Hanisch FG, Rubinstein DB, Wreschner DH. Chalick M, et al. Among authors: rubinstein db. PLoS One. 2016 Oct 21;11(10):e0165031. doi: 10.1371/journal.pone.0165031. eCollection 2016. PLoS One. 2016. PMID: 27768738 Free PMC article.
The MUC1 SEA module is a self-cleaving domain.
Levitin F, Stern O, Weiss M, Gil-Henn C, Ziv R, Prokocimer Z, Smorodinsky NI, Rubinstein DB, Wreschner DH. Levitin F, et al. Among authors: rubinstein db. J Biol Chem. 2005 Sep 30;280(39):33374-86. doi: 10.1074/jbc.M506047200. Epub 2005 Jun 29. J Biol Chem. 2005. PMID: 15987679 Free article.
37 results