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Crystal structure, stability and in vitro RNAi activity of oligoribonucleotides containing the ribo-difluorotoluyl nucleotide: insights into substrate requirements by the human RISC Ago2 enzyme.
Li F, Pallan PS, Maier MA, Rajeev KG, Mathieu SL, Kreutz C, Fan Y, Sanghvi J, Micura R, Rozners E, Manoharan M, Egli M. Li F, et al. Among authors: rozners e. Nucleic Acids Res. 2007;35(19):6424-38. doi: 10.1093/nar/gkm664. Epub 2007 Sep 18. Nucleic Acids Res. 2007. PMID: 17881374 Free PMC article.
Amides as excellent mimics of phosphate linkages in RNA.
Selvam C, Thomas S, Abbott J, Kennedy SD, Rozners E. Selvam C, et al. Among authors: rozners e. Angew Chem Int Ed Engl. 2011 Feb 25;50(9):2068-70. doi: 10.1002/anie.201007012. Epub 2011 Jan 21. Angew Chem Int Ed Engl. 2011. PMID: 21344553 Free PMC article. No abstract available.
Unique gene-silencing and structural properties of 2'-fluoro-modified siRNAs.
Manoharan M, Akinc A, Pandey RK, Qin J, Hadwiger P, John M, Mills K, Charisse K, Maier MA, Nechev L, Greene EM, Pallan PS, Rozners E, Rajeev KG, Egli M. Manoharan M, et al. Among authors: rozners e. Angew Chem Int Ed Engl. 2011 Mar 1;50(10):2284-8. doi: 10.1002/anie.201006519. Epub 2011 Jan 31. Angew Chem Int Ed Engl. 2011. PMID: 21351337 Free PMC article. No abstract available.
Synthesis and properties of triazole-linked RNA.
Mutisya D, Selvam C, Kennedy SD, Rozners E. Mutisya D, et al. Among authors: rozners e. Bioorg Med Chem Lett. 2011 Jun 1;21(11):3420-2. doi: 10.1016/j.bmcl.2011.03.111. Epub 2011 Apr 5. Bioorg Med Chem Lett. 2011. PMID: 21524577 Free PMC article.
85 results