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NF-E2-related factor 2 activation boosts antioxidant defenses and ameliorates inflammatory and amyloid properties in human Presenilin-1 mutated Alzheimer's disease astrocytes.
Oksanen M, Hyötyläinen I, Trontti K, Rolova T, Wojciechowski S, Koskuvi M, Viitanen M, Levonen AL, Hovatta I, Roybon L, Lehtonen Š, Kanninen KM, Hämäläinen RH, Koistinaho J. Oksanen M, et al. Among authors: roybon l. Glia. 2020 Mar;68(3):589-599. doi: 10.1002/glia.23741. Epub 2019 Oct 31. Glia. 2020. PMID: 31670864 Free PMC article.
Unique signatures of stress-induced senescent human astrocytes.
Simmnacher K, Krach F, Schneider Y, Alecu JE, Mautner L, Klein P, Roybon L, Prots I, Xiang W, Winner B. Simmnacher K, et al. Among authors: roybon l. Exp Neurol. 2020 Dec;334:113466. doi: 10.1016/j.expneurol.2020.113466. Epub 2020 Sep 17. Exp Neurol. 2020. PMID: 32949572 Free article.
Proteomic analysis across patient iPSC-based models and human post-mortem hippocampal tissue reveals early cellular dysfunction and progression of Alzheimer's disease pathogenesis.
Pomeshchik Y, Velasquez E, Gil J, Klementieva O, Gidlöf R, Sydoff M, Bagnoli S, Nacmias B, Sorbi S, Westergren-Thorsson G, Gouras GK, Rezeli M, Roybon L. Pomeshchik Y, et al. Among authors: roybon l. Acta Neuropathol Commun. 2023 Sep 15;11(1):150. doi: 10.1186/s40478-023-01649-z. Acta Neuropathol Commun. 2023. PMID: 37715247 Free PMC article.
Generation of human pluripotent stem cell reporter lines for the isolation of and reporting on astrocytes generated from ventral midbrain and ventral spinal cord neural progenitors.
Holmqvist S, Brouwer M, Djelloul M, Diaz AG, Devine MJ, Hammarberg A, Fog K, Kunath T, Roybon L. Holmqvist S, et al. Among authors: roybon l. Stem Cell Res. 2015 Jul;15(1):203-20. doi: 10.1016/j.scr.2015.05.014. Epub 2015 Jun 6. Stem Cell Res. 2015. PMID: 26100233 Free article.
65 results