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The PI3K-Akt-mTOR and Associated Signaling Pathways as Molecular Drivers of Immune-Mediated Inflammatory Skin Diseases: Update on Therapeutic Strategy Using Natural and Synthetic Compounds.
Roy T, Boateng ST, Uddin MB, Banang-Mbeumi S, Yadav RK, Bock CR, Folahan JT, Siwe-Noundou X, Walker AL, King JA, Buerger C, Huang S, Chamcheu JC. Roy T, et al. Cells. 2023 Jun 20;12(12):1671. doi: 10.3390/cells12121671. Cells. 2023. PMID: 37371141 Free PMC article. Review.
Synthesis, inverse docking-assisted identification and in vitro biological characterization of Flavonol-based analogs of fisetin as c-Kit, CDK2 and mTOR inhibitors against melanoma and non-melanoma skin cancers.
Roy T, Boateng ST, Banang-Mbeumi S, Singh PK, Basnet P, Chamcheu RN, Ladu F, Chauvin I, Spiegelman VS, Hill RA, Kousoulas KG, Nagalo BM, Walker AL, Fotie J, Murru S, Sechi M, Chamcheu JC. Roy T, et al. Bioorg Chem. 2021 Feb;107:104595. doi: 10.1016/j.bioorg.2020.104595. Epub 2020 Dec 30. Bioorg Chem. 2021. PMID: 33450548 Free PMC article.
Identification of new fisetin analogs as kinase inhibitors: Data on synthesis and anti-skin cancer activities evaluation.
Roy T, Boateng ST, Banang-Mbeumi S, Singh PK, Basnet P, Chamcheu RN, Ladu F, Chauvin I, Spiegelman VS, Hill RA, Kousoulas KG, Nagalo BM, Walker AL, Fotie J, Murru S, Sechi M, Chamcheu JC. Roy T, et al. Data Brief. 2021 Feb 10;35:106858. doi: 10.1016/j.dib.2021.106858. eCollection 2021 Apr. Data Brief. 2021. PMID: 33665254 Free PMC article.
Synthesis, in silico modelling, and in vitro biological evaluation of substituted pyrazole derivatives as potential anti-skin cancer, anti-tyrosinase, and antioxidant agents.
Boateng ST, Roy T, Torrey K, Owunna U, Banang-Mbeumi S, Basnet D, Niedda E, Alexander AD, Hage DE, Atchimnaidu S, Nagalo BM, Aryal D, Findley A, Seeram NP, Efimova T, Sechi M, Hill RA, Ma H, Chamcheu JC, Murru S. Boateng ST, et al. Among authors: roy t. J Enzyme Inhib Med Chem. 2023 Dec;38(1):2205042. doi: 10.1080/14756366.2023.2205042. J Enzyme Inhib Med Chem. 2023. PMID: 37184042 Free PMC article.
1,307 results