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Acquired resistance to KRAS G12C small-molecule inhibitors via genetic/nongenetic mechanisms in lung cancer.
Mohanty A, Nam A, Srivastava S, Jones J, Lomenick B, Singhal SS, Guo L, Cho H, Li A, Behal A, Mirzapoiazova T, Massarelli E, Koczywas M, Arvanitis LD, Walser T, Villaflor V, Hamilton S, Mambetsariev I, Sattler M, Nasser MW, Jain M, Batra SK, Soldi R, Sharma S, Fakih M, Mohanty SK, Mainan A, Wu X, Chen Y, He Y, Chou TF, Roy S, Orban J, Kulkarni P, Salgia R. Mohanty A, et al. Among authors: roy s. Sci Adv. 2023 Oct 13;9(41):eade3816. doi: 10.1126/sciadv.ade3816. Epub 2023 Oct 13. Sci Adv. 2023. PMID: 37831779 Free PMC article.
Structural and Dynamical Order of a Disordered Protein: Molecular Insights into Conformational Switching of PAGE4 at the Systems Level.
Lin X, Kulkarni P, Bocci F, Schafer NP, Roy S, Tsai MY, He Y, Chen Y, Rajagopalan K, Mooney SM, Zeng Y, Weninger K, Grishaev A, Onuchic JN, Levine H, Wolynes PG, Salgia R, Rangarajan G, Uversky V, Orban J, Jolly MK. Lin X, et al. Among authors: roy s. Biomolecules. 2019 Feb 22;9(2):77. doi: 10.3390/biom9020077. Biomolecules. 2019. PMID: 30813315 Free PMC article.
Protein conformational dynamics and phenotypic switching.
Kulkarni P, Achuthan S, Bhattacharya S, Jolly MK, Kotnala S, Leite VBP, Mohanty A, Orban J, Roy S, Rangarajan G, Salgia R. Kulkarni P, et al. Among authors: roy s. Biophys Rev. 2021 Nov 27;13(6):1127-1138. doi: 10.1007/s12551-021-00858-x. eCollection 2021 Dec. Biophys Rev. 2021. PMID: 35059032 Free PMC article. Review.
Intrinsically disordered proteins: Ensembles at the limits of Anfinsen's dogma.
Kulkarni P, Leite VBP, Roy S, Bhattacharyya S, Mohanty A, Achuthan S, Singh D, Appadurai R, Rangarajan G, Weninger K, Orban J, Srivastava A, Jolly MK, Onuchic JN, Uversky VN, Salgia R. Kulkarni P, et al. Among authors: roy s. Biophys Rev (Melville). 2022 Mar 17;3(1):011306. doi: 10.1063/5.0080512. eCollection 2022 Mar. Biophys Rev (Melville). 2022. PMID: 38505224 Free PMC article. Review.
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