Rowley B - Search Results

1

BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis.

Wilhelm SM, Carter C, Tang L, Wilkie D, McNabola A, Rong H, Chen C, Zhang X, Vincent P, McHugh M, Cao Y, Shujath J, Gawlak S, Eveleigh D, Rowley B, Liu L, Adnane L, Lynch M, Auclair D, Taylor I, Gedrich R, Voznesensky A, Riedl B, Post LE, Bollag G, Trail PA. Wilhelm SM, et al. Among authors: rowley b. Cancer Res. 2004 Oct 1;64(19):7099-109. doi: 10.1158/0008-5472.CAN-04-1443. Cancer Res. 2004. PMID: 15466206

2

BAY 80-6946 is a highly selective intravenous PI3K inhibitor with potent p110α and p110δ activities in tumor cell lines and xenograft models.

Liu N, Rowley BR, Bull CO, Schneider C, Haegebarth A, Schatz CA, Fracasso PR, Wilkie DP, Hentemann M, Wilhelm SM, Scott WJ, Mumberg D, Ziegelbauer K. Liu N, et al. Mol Cancer Ther. 2013 Nov;12(11):2319-30. doi: 10.1158/1535-7163.MCT-12-0993-T. Epub 2013 Oct 29. Mol Cancer Ther. 2013. PMID: 24170767

3

Tumor development by transgenic expression of a constitutively active insulin-like growth factor I receptor.

Carboni JM, Lee AV, Hadsell DL, Rowley BR, Lee FY, Bol DK, Camuso AE, Gottardis M, Greer AF, Ho CP, Hurlburt W, Li A, Saulnier M, Velaparthi U, Wang C, Wen ML, Westhouse RA, Wittman M, Zimmermann K, Rupnow BA, Wong TW. Carboni JM, et al. Cancer Res. 2005 May 1;65(9):3781-7. doi: 10.1158/0008-5472.CAN-04-4602. Cancer Res. 2005. PMID: 15867374

4

Constitutively active receptor tyrosine kinases as oncogenes in preclinical models for cancer therapeutics.

Kellar KA, Lorenzi MV, Ho CP, You D, Wen ML, Ryseck RP, Oppenheimer S, Fink BE, Vite GD, Rowley BR, Yu C, Bol DK, Lee FY, Wong TW. Kellar KA, et al. Mol Cancer Ther. 2006 Jun;5(6):1571-6. doi: 10.1158/1535-7163.MCT-06-0078. Mol Cancer Ther. 2006. PMID: 16818516

5

Disruption of epithelial gamma delta T cell repertoires by mutation of the Syk tyrosine kinase.

Mallick-Wood CA, Pao W, Cheng AM, Lewis JM, Kulkarni S, Bolen JB, Rowley B, Tigelaar RE, Pawson T, Hayday AC. Mallick-Wood CA, et al. Among authors: rowley b. Proc Natl Acad Sci U S A. 1996 Sep 3;93(18):9704-9. doi: 10.1073/pnas.93.18.9704. Proc Natl Acad Sci U S A. 1996. PMID: 8790395 Free PMC article.

6

Syk tyrosine kinase required for mouse viability and B-cell development.

Cheng AM, Rowley B, Pao W, Hayday A, Bolen JB, Pawson T. Cheng AM, et al. Among authors: rowley b. Nature. 1995 Nov 16;378(6554):303-6. doi: 10.1038/378303a0. Nature. 1995. PMID: 7477353

7

COVID-19 and abnormal uterine bleeding: potential associations and mechanisms.

Maybin JA, Watters M, Rowley B, Walker CA, Sharp GC, Alvergne A. Maybin JA, et al. Among authors: rowley b. Clin Sci (Lond). 2024 Feb 21;138(4):153-171. doi: 10.1042/CS20220280. Clin Sci (Lond). 2024. PMID: 38372528 Free PMC article. Review.

8

On the Use of Triarylsilanols as Catalysts for Direct Amidation of Carboxylic Acids.

Braddock DC, Rowley BC, Lickiss PD, Fussell SJ, Qamar R, Pugh D, Rzepa HS, White AJP. Braddock DC, et al. Among authors: rowley bc. J Org Chem. 2023 Jul 21;88(14):9853-9869. doi: 10.1021/acs.joc.3c00585. Epub 2023 Jul 11. J Org Chem. 2023. PMID: 37432502 Free PMC article.

9

Identification of ligand linkage vectors for the development of p300/CBP degraders.

Brownsey DK, Rowley BC, Gorobets E, Mihara K, Maity R, Papatzimas JW, Gelfand BS, Hollenberg MD, Bahlis NJ, Derksen DJ. Brownsey DK, et al. Among authors: rowley bc. RSC Med Chem. 2022 Apr 14;13(6):726-730. doi: 10.1039/d1md00070e. eCollection 2022 Jun 22. RSC Med Chem. 2022. PMID: 35814928 Free PMC article.

10

Regioselective Synthesis of C3-Hydroxyarylated Pyrazoles.

O'Sullivan L, Patel KV, Rowley BC, Brownsey DK, Gorobets E, Gelfand BS, Van Humbeck JF, Derksen DJ. O'Sullivan L, et al. Among authors: rowley bc. J Org Chem. 2022 Jan 7;87(1):846-854. doi: 10.1021/acs.joc.1c02518. Epub 2021 Dec 14. J Org Chem. 2022. PMID: 34905376

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