Rowlett J - Search Results

1

Hydrochloride Salt of the GABAkine KRM-II-81.

Mian MY, Divović B, Sharmin D, Pandey KP, Golani LK, Tiruveedhula VVNPB, Cerne R, Smith JL, Ping X, Jin X, Imler GH, Deschamps JR, Lippa A, Cook JM, Savić MM, Rowlett J, Witkin JM. Mian MY, et al. Among authors: rowlett j. ACS Omega. 2022 Jul 27;7(31):27550-27559. doi: 10.1021/acsomega.2c03029. eCollection 2022 Aug 9. ACS Omega. 2022. PMID: 35967038 Free PMC article.

2

Selective antagonism of GABAA receptor subtypes: an in vivo approach to exploring the therapeutic and side effects of benzodiazepine-type drugs.

Rowlett JK, Cook JM, Duke AN, Platt DM. Rowlett JK, et al. CNS Spectr. 2005 Jan;10(1):40-8. doi: 10.1017/s1092852900009895. CNS Spectr. 2005. PMID: 15618946 Review.

3

A study of the structure-activity relationship of GABA(A)-benzodiazepine receptor bivalent ligands by conformational analysis with low temperature NMR and X-ray analysis.

Han D, Holger Försterling F, Li X, Deschamps JR, Parrish D, Cao H, Rallapalli S, Clayton T, Teng Y, Majumder S, Sankar S, Roth BL, Sieghart W, Furtmuller R, Rowlett JK, Weed MR, Cook JM. Han D, et al. Bioorg Med Chem. 2008 Oct 1;16(19):8853-62. doi: 10.1016/j.bmc.2008.08.072. Epub 2008 Sep 2. Bioorg Med Chem. 2008. PMID: 18790643 Free PMC article.

4

Antagonism of triazolam self-administration in rhesus monkeys responding under a progressive-ratio schedule: In vivo apparent pA2 analysis.

Fischer BD, Platt DM, Rallapalli SK, Namjoshi OA, Cook JM, Rowlett JK. Fischer BD, et al. Drug Alcohol Depend. 2016 Jan 1;158:22-9. doi: 10.1016/j.drugalcdep.2015.10.026. Epub 2015 Oct 30. Drug Alcohol Depend. 2016. PMID: 26596587 Free PMC article.

5

A Review of the Updated Pharmacophore for the Alpha 5 GABA(A) Benzodiazepine Receptor Model.

Clayton T, Poe MM, Rallapalli S, Biawat P, Savić MM, Rowlett JK, Gallos G, Emala CW, Kaczorowski CC, Stafford DC, Arnold LA, Cook JM. Clayton T, et al. Int J Med Chem. 2015;2015:430248. doi: 10.1155/2015/430248. Epub 2015 Nov 10. Int J Med Chem. 2015. PMID: 26682068 Free PMC article. Review.

6

Evidence That Sedative Effects of Benzodiazepines Involve Unexpected GABA_A Receptor Subtypes: Quantitative Observation Studies in Rhesus Monkeys.

Duke AN, Meng Z, Platt DM, Atack JR, Dawson GR, Reynolds DS, Tiruveedhula VVNPB, Li G, Stephen MR, Sieghart W, Cook JM, Rowlett JK. Duke AN, et al. J Pharmacol Exp Ther. 2018 Jul;366(1):145-157. doi: 10.1124/jpet.118.249250. Epub 2018 May 2. J Pharmacol Exp Ther. 2018. PMID: 29720564 Free PMC article.

7

The α2,3-selective potentiator of GABA_A receptors, KRM-II-81, reduces nociceptive-associated behaviors induced by formalin and spinal nerve ligation in rats.

Witkin JM, Cerne R, Davis PG, Freeman KB, do Carmo JM, Rowlett JK, Methuku KR, Okun A, Gleason SD, Li X, Krambis MJ, Poe M, Li G, Schkeryantz JM, Jahan R, Yang L, Guo W, Golani LK, Anderson WH, Catlow JT, Jones TM, Porreca F, Smith JL, Knopp KL, Cook JM. Witkin JM, et al. Among authors: rowlett jk. Pharmacol Biochem Behav. 2019 May;180:22-31. doi: 10.1016/j.pbb.2019.02.013. Epub 2019 Feb 27. Pharmacol Biochem Behav. 2019. PMID: 30825491 Free PMC article.

8

GABA_A Receptor Subtypes and the Abuse-Related Effects of Ethanol in Rhesus Monkeys: Experiments with Selective Positive Allosteric Modulators.

Berro LF, Rüedi-Bettschen D, Cook JE, Golani LK, Li G, Jahan R, Rashid F, Cook JM, Rowlett JK, Platt DM. Berro LF, et al. Alcohol Clin Exp Res. 2019 May;43(5):791-802. doi: 10.1111/acer.14000. Epub 2019 Apr 8. Alcohol Clin Exp Res. 2019. PMID: 30861153 Free PMC article.

9

Evaluation of the anti-conflict, reinforcing, and sedative effects of YT-III-31, a ligand functionally selective for α3 subunit-containing GABA_A receptors.

Meng Z, Berro LF, Sawyer EK, Rüedi-Bettschen D, Cook JE, Li G, Platt DM, Cook JM, Rowlett JK. Meng Z, et al. J Psychopharmacol. 2020 Mar;34(3):348-357. doi: 10.1177/0269881119882803. Epub 2019 Oct 31. J Psychopharmacol. 2020. PMID: 31670615 Free PMC article.

10

8-Substituted Triazolobenzodiazepines: In Vitro and In Vivo Pharmacology in Relation to Structural Docking at the α1 Subunit-Containing GABA_A Receptor.

Golani LK, Platt DM, Rüedi-Bettschen D, Edwanker C, Huang S, Poe MM, Furtmüller R, Sieghart W, Cook JM, Rowlett JK. Golani LK, et al. Front Pharmacol. 2021 Apr 20;12:625233. doi: 10.3389/fphar.2021.625233. eCollection 2021. Front Pharmacol. 2021. PMID: 33959005 Free PMC article.

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